Results 21 to 30 of about 137,214 (262)

High proliferative activity of Reed Sternberg associated antigen Ki-1 positive cells in normal lymphoid tissue. [PDF]

open access: yesJournal of Clinical Pathology, 1986
An improved immunoenzymatic double labelling method was developed, which simultaneously shows the Ki-1 membrane antigen and the nuclear proliferation associated antigen, defined by monoclonal antibody Ki-67. This new approach permits in situ discrimination of cells that are proliferating or not with a particular membrane antigen.
J, Gerdes, R, Schwarting, H, Stein
openaire   +2 more sources

Ki-67 immuno-histochemistry index in stage III giant cell tumor of the bone

open access: yesJournal of Experimental & Clinical Cancer Research, 2010
Background Giant cell tumor is an infrequent and unpredictable bony lesion. Although numerous attempts have been made to predict the behaviour of GCT, there are no definite biological or histological parameters to determine the prognosis or ...
Daud Salzihan M   +4 more
doaj   +1 more source

Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment

open access: yesFrontiers in Microbiology, 2022
BackgroundCurrent blood-based diagnostic tools for TB are insufficient to properly characterize the distinct stages of TB, from the latent infection (LTBI) to its active form (aTB); nor can they assess treatment efficacy.
Sergio Díaz-Fernández   +31 more
doaj   +1 more source

Correlation of p53 and KI-67 expression with grade and subtype of ependymoma

open access: yesIndian Journal of Pathology and Microbiology, 2012
Introduction: The morphological criteria for grading ependymomas were always felt subjective. Recently some studies have showed that Ki-67 and p53 immunolabeling are important prognostic markers in ependymomas.
Lakshmi P Manasa, M S Uppin, C Sundaram
doaj   +1 more source

Evaluation of the expression of Bmi-1 stem cell marker in sinonasal melanomas and its correlation with the expression of cell cycle proteins

open access: yesSurgical and Experimental Pathology, 2019
Background Sinonasal melanomas (SNM) are aggressive neoplasms, which present distinct clinicopathological and molecular aspects when compared to cutaneous melanomas (CM).
Harim Tavares dos Santos   +8 more
doaj   +1 more source

The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus

open access: yesAdvances in Rheumatology, 2023
Background The defect of B cell self-tolerance and the continuous antigen presentation by T cells (TCs) mediated by autoreactive B cells (BCs) play a key role in the occurrence and development of systemic lupus erythematosus (SLE).
Zhuobei Xie   +10 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Lack of correlation between Ki-67 labelling index and tumor size of anterior pituitary adenomas

open access: yesBMC Cancer, 2001
Aims and background The Ki-67 is a nuclear antigen detected by the monoclonal antibody MIB-1 and its Labeling Index (LI) is considered a marker of normal and abnormal cell proliferation.
Guiducci Antonio   +2 more
doaj   +1 more source

Pathomorphological and immunohistochemical features of the esophageal mucosa in children with asthma combined with reflux esophagitis

open access: yesPatologìâ, 2021
The most common comorbid pathology in children with asthma is gastroesophageal reflux disease (GERD) associated with reflux esophagitis (RE), which ranges from 32 % to 80 %.
T. D. Zadorozhna   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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