Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis. [PDF]
Blood, 2015 Key Points In a majority of patients with advanced SM, neoplastic MCs express the target receptor CD30. The CD30-targeting drug brentuximab-vedotin blocks growth and survival in CD30+ neoplastic MCs which favors drug development in advanced SM.
Blatt K +17 more
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Blatt K, Cerny-Reiterer S, Schwaab J, et al. Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis. Blood. 2015;126(26):2832-2841. [PDF]
Blood, 2018 europepmc +3 more sources
Expression of Ki-1 antigen (CD30) in mesenchymal tumors [PDF]
Cancer, 1990 Expression of CD30(Ki-1) antigen has long been considered to be restricted to activated lymphocytes and related tumors. However, expression of this antigen has also been detected in embryonal carcinomas, in nonembryonal carcinomas, in malignant melanomas, and even in some myeloid cell lines and macrophages at late stages of differentiation.
G, Mechtersheimer, P, Möller
openaire +2 more sources
Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma
European Journal of Histochemistry, 2022 The cancer/testis antigens (CTAs), New York esophageal squamous cell carcinoma-1 (NY-ESO-1) and melanoma antigen gene (MAGE)-A4 are normally restricted to male germ cells but are aberrantly expressed in several cancers.
Kazuhiko Hashimoto +5 more
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Radiomic prediction models for the level of Ki-67 and p53 in glioma
Journal of International Medical Research, 2020 Objective To identify glioma radiomic features associated with proliferation-related Ki-67 antigen and cellular tumour antigen p53 levels, common immunohistochemical markers for differentiating benign from malignant tumours, and to generate radiomic ...
Xiaojun Sun +5 more
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Data on clinical significance of GAS2 in colorectal cancer cells
Data in Brief, 2016 The growth arrest-specific 2 (GAS2) was cloned and found to be upregulated in the feces of recurrent CRC patients. This overexpressed GAS2 induced different patterns of gene expressions in CRC cells. Briefly, one cell proliferation marker, Ki-67 antigen (
Chun-Chao Chang +5 more
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Diagnostic and Prognostic Significance of Ki-67 Immunohistochemical Expression in Surface Epithelial Ovarian Carcinoma [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: The Surface Epithelial Ovarian Carcinoma (SEOC) at the moment of diagnosis, the disease is extended beyond the structures of the pelvis. Ki-67 is one of the prognostic marker which determines the growth fraction of a tumour and its over
Asha Mahadevappa +2 more
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Measurement of Ki-67 antigen in 159 pituitary adenomas using the MIB-1 monoclonal antibody
Brazilian Journal of Medical and Biological Research, 2004 Pituitary adenomas sometimes show rapid growth and recurrence, and about one third invade the structures surrounding the sella turcica. In an attempt to determine aggressive behavior at an early stage, we used the MIB-1 antibody to identify the Ki-67 ...
C.B. Pizarro +3 more
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Advanced Science, 2023 The robust and stable expression of CD38 in T‐cell acute lymphoblastic leukemia (T‐ALL) blasts makes CD38 chimeric antigen receptor (CAR)‐T/natural killer (NK) a potential therapy for T‐ALL. However, CD38 expression in normal T/NK cells causes fratricide
Chan Liao +14 more
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Prognostic Value of Ki 67 Proliferation Antigen in Canine Malignant Mammary Gland Tumours
Brazilian Journal of Veterinary Pathology, 2011 Canine malignant mammary gland tumours were surgically resected from 78 dogs to determine the prognostic value of Ki 67 Proliferation antigen. After post surgical follow up for minimum of 1 year, 48 dogs were still alive, while 21 dogs had died as a ...
Jayachandra C. Kadthur +4 more
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