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Ki-67 Expression in Vulvar Carcinoma
International Journal of Gynecological Pathology, 1994The proliferative activity of invasive squamous cell carcinoma of the vulva was examined using a Ki-67 equivalent monoclonal antibody (MIB1), which gives a strong immunoreaction in paraffin-embedded tissue. Quantitation of Ki-67 immunostaining was accomplished by image analysis. Ki-67 immunostaining revealed two general patterns of reactivity in vulvar
J B, Hendricks +5 more
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Neurosurgery, 2009
KI-67, A MARKER of cellular proliferation, has been studied extensively in pituitary neoplasia. It is of relevance to various clinicopathological parameters, including tumor subtype, size, invasiveness, and recurrence, as well as patient age and sex. Generally, pituitary tumors behaving aggressively have increased Ki-67 labeling indices.
Fateme, Salehi +5 more
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KI-67, A MARKER of cellular proliferation, has been studied extensively in pituitary neoplasia. It is of relevance to various clinicopathological parameters, including tumor subtype, size, invasiveness, and recurrence, as well as patient age and sex. Generally, pituitary tumors behaving aggressively have increased Ki-67 labeling indices.
Fateme, Salehi +5 more
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Oral Oncology, 2010
To analyze the prognostic value of Ki-67 in oral cancer and its relationship with Ki-67 expression in precancerous epithelium.We studied 79 tumors from 65 patients. Immunohistochemistry study with Mib-1 monoclonal antibody was used to detect Ki-67 expression in tumor tissue and adjacent non-tumor tissue. The influence of different variables on survival
M A, Gonzalez-Moles +4 more
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To analyze the prognostic value of Ki-67 in oral cancer and its relationship with Ki-67 expression in precancerous epithelium.We studied 79 tumors from 65 patients. Immunohistochemistry study with Mib-1 monoclonal antibody was used to detect Ki-67 expression in tumor tissue and adjacent non-tumor tissue. The influence of different variables on survival
M A, Gonzalez-Moles +4 more
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Ki‐67 and p53 in T2 laryngeal cancer
The Laryngoscope, 1998AbstractObjective: To study the relationship between the proliferative capacity, represented by the immunohistochemical labeling index (LI) of proliferation marker Ki‐67, and the p53 status, as in theory an intact p53 cell cycle checkpoint system should result in a lower proliferative capacity.
A, Kropveld +4 more
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Ki-67 is an indicator of progression of neuroendocrine tumors
Endocrine Pathology, 1994No current histological or cytological indices can distinguish reliably malignant from benign tumors in neuroendocrine tumors, including pheochromocytomas, pancreatic endocrine tumors, and carcinoid tumors. We investigated immunohistochemically the expression of Ki-67 in 52 neuroendocrine tumors, including 17 pheochromocytomas, 9 pancreatic endocrine ...
Noriko, Kimura +5 more
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The Ki-67 protein: From the known and the unknown
Journal of Cellular Physiology, 2000The expression of the human Ki-67 protein is strictly associated with cell proliferation. During interphase, the antigen can be exclusively detected within the nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes.
T, Scholzen, J, Gerdes
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Ki‐67 and grading of malignant fibrous histiocytomas
Cancer, 1990Although generally considered to be of high grade, malignant fibrous histiocytomas (MFH) show a range of histologic appearances and a diverse biologic behavior. More precise grading of this type of sarcoma is desirable. The rate of cell proliferation may reflect clinical behavior.
R J, Zehr +3 more
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Ki-67 immunostaining and prognosis in laryngeal cancer
Clinical Otolaryngology and Allied Sciences, 1998The expression of the antigen defined by the Ki-67 antibody in paraffin sections from 154 biopsies of laryngeal squamous cell carcinomas was examined. There was a significant difference in Ki-67 expression between the control group and the patients with cancer (P < 0.001). There was no significant difference in the Ki-67 score between the patients with
T, Krecicki +3 more
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Restricted Expression of Ki-67 in Cholesteatoma Epithelium
Archives of Otolaryngology - Head and Neck Surgery, 1993Proliferative sites within the overgrowing epithelium of cholesteatoma are still ill defined. In this study, we used the monoclonal antibody Ki-67 on frozen cut sections from 23 cholesteatoma samples obtained at surgery from 20 patients. This reagent has been reported to stain the nucleus of proliferating tumor cells and the cytoplasm of growing ...
D, Mayot +3 more
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2018
Objective: to study peculiarities of the course of breast cancer (BC) with Ki-67 overexpression depending on the area occupied by the tumor stroma. Object and methods: the study included 220 patients with BC (T1N0M0 ??? 19, T2N0M0, T1N1M0 ??? 90, T2N1M0, T3N0M0 ??? 98, T4N0M0 ??? 13).
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Objective: to study peculiarities of the course of breast cancer (BC) with Ki-67 overexpression depending on the area occupied by the tumor stroma. Object and methods: the study included 220 patients with BC (T1N0M0 ??? 19, T2N0M0, T1N1M0 ??? 90, T2N1M0, T3N0M0 ??? 98, T4N0M0 ??? 13).
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