The cell proliferation antigen Ki-67 organises heterochromatin
eLife, 2016 Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 controls heterochromatin organisation.
Michal Sobecki +20 more
doaj +7 more sources
Ki-67 Antigen Overexpression Is Associated with the Metaplasia-Adenocarcinoma Sequence in Barrett's Esophagus [PDF]
Gastroenterology Research and Practice, 2012 Introduction. The objective of this study was to evaluate Ki-67 antigen expression in patients with Barrett’s esophagus and esophageal adenocarcinoma and to assess its correlation with the metaplasia-esophageal adenocarcinoma progression. Methods.
Bernardo Silveira Volkweis +5 more
doaj +2 more sources
Ki-67 Antigen; A Valuable Prognostic Biomarker for Chronic Lymphocytic Leukemia [PDF]
مجله دانشکده پزشکی اصفهان, 2022 Background: Chronic lymphocytic leukemia (CLL) is one of the most common blood malignancies. The chief cells involved in this malignancy are in the G0 phase of cell division and have no proliferative activity; however, what determines the severity and ...
Valiollah Mehrzad, Samaneh Madadi
doaj +2 more sources
Ki-67 expression in squamous intraepithelial lesions of the uterine cervix [PDF]
Archive of Oncology, 2006 BACKGROUND: Uncontrolled cell proliferation and malignant transformation are the basic elements in the development of malignant disease including cervical cancer and its precursors.
Panjković Milana +1 more
doaj +3 more sources
Cigarette Smoking, Oncogenic Human Papillomavirus, Ki-67 Antigen, and Cervical Intraepithelial Neoplasia [PDF]
American Journal of Epidemiology, 2004 Although cigarette smoking has been identified as a cofactor for cervical neoplasia, it is not clear whether smoking exerts an early or late effect on the evolution of human papillomavirus (HPV)-related lesions. A case-control study of Washington State women who presented for routine gynecologic care from 1997 to 2001 was conducted. All women underwent
Tiffany G. Harris
openalex +3 more sources
Expression of Metallothionein I/II and Ki-67 Antigen in Graves' Disease [PDF]
Anticancer Research, 2018 The expression of metallothionein I/II (MT-I/II) was examined in thyroids of Graves' disease (GD) and nodular goiter (NG) patients to determine its role as a potential marker of proliferation and autoimmune inflammation in the thyroid.MT-I/II and Ki-67 antigen expression was studied using immunohistochemistry in 72 GD and 24 NG patients.MT-I/II ...
Paweł Domosławski +6 more
openalex +3 more sources
Vascular Endothelial Growth Factor and Ki-67 Antigen Expression in Relation to Age and Gender in Oral Squamous Cell Carcinoma [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2012 Background and aims. Vascular endothelial growth factor (VEGF) and Ki-67 antigen are contributing factors in this process cell proliferation and new blood vessels formation in tumor progression.
Noushin Jalayer Naderi +4 more
doaj +2 more sources
In Response to "Intratumor Distribution of Ki-67 Antigen Beyond Labeling Index for Clinical Decision Making: A New Way of Counting". [PDF]
JTO Clin Res Rep, 2021 Belderbos RA +2 more
europepmc +3 more sources
Expression of Ki-67—–A Proliferation-Associated Antigen—in Prostatic Cancer
Acta Oncologica, 1991 The expression of the proliferation-associated antigen Ki-67 was studied in human prostatic cancer. The antigen was analyzed with an immuno-histochemical technique in TUR specimens. A correlation was seen between Ki-67 positivity and differentiation grade. All TUR specimens (15/15) with poorly differentiated carcinomas expressed the antigen. Moderately
Sten Nilsson +3 more
openalex +3 more sources