Results 1 to 10 of about 94,068 (259)

Ki-67 Antigen Overexpression Is Associated with the Metaplasia-Adenocarcinoma Sequence in Barrett's Esophagus [PDF]

Gastroenterology Research and Practice, 2012
Introduction. The objective of this study was to evaluate Ki-67 antigen expression in patients with Barrett’s esophagus and esophageal adenocarcinoma and to assess its correlation with the metaplasia-esophageal adenocarcinoma progression. Methods.
Bernardo Silveira Volkweis, Richard Ricachenevsky Gurski, Luise Meurer, Guilherme Gonçalves Pretto, Guilherme da Silva Mazzini, Maria Isabel Edelweiss   +5 more
doaj   +5 more sources

The cell proliferation antigen Ki-67 organises heterochromatin

eLife, 2016
Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 controls heterochromatin organisation.
Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas, David Llères, François Gerbe, Susana Prieto, Liliana Krasinska, Alexandre David, Manuel Eguren, Marie-Christine Birling, Serge Urbach, Sonia Hem, Jérôme Déjardin, Marcos Malumbres, Philippe Jay, Vjekoslav Dulic, Denis LJ Lafontaine, Robert Feil, Daniel Fisher   +20 more
doaj   +7 more sources

Ki-67 staining pattern as a prognostic biomarker for advanced acral melanoma [PDF]

Anais Brasileiros de Dermatologia
Background Acral cutaneous melanoma (ACM) is an aggressive skin cancer, especially when diagnosed in the advanced stage. The Ki-67 is a rapid tool for proliferation rate analysis.
Marcel Arakaki Asato, Isabeli Joaquim Contel, Francisco Alves Moraes Neto, Juliana Polizel Ocanha-Xavier, Nathália Silva Carlos Oliveira, Maxwell A. Fung, Mariangela Esther Alencar Marques, José Cândido Caldeira Xavier-Júnior   +7 more
doaj   +3 more sources

Ki-67 Antigen; A Valuable Prognostic Biomarker for Chronic Lymphocytic Leukemia [PDF]

مجله دانشکده پزشکی اصفهان, 2022
Background: Chronic lymphocytic leukemia (CLL) is one of the most common blood malignancies. The chief cells involved in this malignancy are in the G0 phase of cell division and have no proliferative activity; however, what determines the severity and ...
Valiollah Mehrzad, Samaneh Madadi
doaj   +1 more source

Obtaining Specific Hybridomas for Ki-67 Protein Immunodetection

Indonesian Biomedical Journal, 2021
BACKGROUND: Active proliferation is specific property of a tumor cells. However, the cost of the analysis is high due to commercial anti-Ki-67 mAbs used as the main immunoreagent for reliable identification of proliferating cells.
Aigerim Turgimbayeva, Sailau Abeldenov, Nurgul Sarina, Bekbolat Khassenov, Saule Eskendirova   +4 more
doaj   +1 more source

MCM5 Expression Is Associated With the Grade of Malignancy and Ki-67 Antigen in LSCC [PDF]

Anticancer Research, 2019
The minichromosome maintenance proteins (MCMs) may be potential biomarkers of cancer cell proliferation. They are essential to initiate DNA replication. The aim of the study was to investigate the level of MCM5 expression in benign lesions (BLs) and laryngeal squamous cell cancer (LSCC).Immunohistochemical (IHC) analysis was carried out on 83 LSCCs and
Katarzyna, Nowinska, Urszula, Ciesielska, Aleksandra, Piotrowska, Karolina, Jablonska, Aleksandra, Partynska, Maria, Paprocka, Tomasz, Zatonski, Marzena, Podhorska-Okolow, Piotr, Dziegiel   +8 more
openaire   +2 more sources

Value of the proliferative and hormonal markers in estimation of biological behaviour of meningioma [PDF]

Archive of Oncology, 2002
(Conclusion) Although the proliferative markers and hormonal (progesterone) receptor status of meningiomas seem to provide useful, convenient, and predictive criterions for the subsequent evolution of the tumor, they should be used only in combination ...
Skender-Gazibara Milica, Cvetković-Dožić Dubravka, Dožić Slobodan, Govedarović Vitomir   +3 more
doaj   +1 more source

Investigation of the histopathological level of Ki-67, caspase-3 expressions of the effects of hesperidin on wound healing in the rat esophagus

Acta Cirúrgica Brasileira, 2023
Purpose: The effects of hesperidin application on the wound caused by esophageal burns were investigated in this study. Methods: Wistar albino rats were divided into three groups: Control group: only 1 mL of 0.09% NaCl was administered i.p. for 28 days;
Cemalettin Durgun, Gülsen Kirman, Engin Deveci   +2 more
doaj   +1 more source

Histochemistry of Ki-67 antigen in ameloblastomas.

Journal of Osaka Dental University, 1999
The proliferative potential of two common histologic variants of ameloblastoma was investigated immunohistochemically using Ki-67 antibody on routinely processed, formalin-fixed, paraffin-embedded sections. Thirty cases of ameloblastomas (15 cases of follicular and 15 cases of plexiform type) were analyzed.
Nagao, Yutaka, Wato, Masahiro, Tanaka, Akio   +2 more
openaire   +3 more sources

Developmental expression of Ki‐67 antigen and proliferating cell nuclear antigen in macaque placentas [PDF]

Developmental Dynamics, 1994
AbstractPlacental growth is largely determined by the proliferation of cytotrophoblast cells. However, the distribution of cytotrophoblast cells engaged in the cell cycle during placental development is poorly understood. Recently, antibodies have been developed that identify two proteins directly involved with DNA synthesis: Ki‐67 protein and ...
T N, Blankenship, B F, King
openaire   +2 more sources