Results 31 to 40 of about 94,380 (259)

Low Ki-67 gene expression in non-neoplastic proliferation of oral mucosal epithelium [PDF]

open access: yesUniversa Medicina, 2012
Background Neoplastic and non-neoplastic oral mucosal growths often have a variety of clinical manifestations according to their biological nature.
Janti Sudiono, Irmawati Hassan
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Measurement of Ki-67 antigen in 159 pituitary adenomas using the MIB-1 monoclonal antibody

open access: yesBrazilian Journal of Medical and Biological Research, 2004
Pituitary adenomas sometimes show rapid growth and recurrence, and about one third invade the structures surrounding the sella turcica. In an attempt to determine aggressive behavior at an early stage, we used the MIB-1 antibody to identify the Ki-67 ...
C.B. Pizarro   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

An immunohistochemical study showing Ki-67 as an analytical marker in oral malignant and premalignant lesions

open access: yesJournal of Pharmacy and Bioallied Sciences, 2020
Introduction: Ki-67 is a nuclear protein. It is a proliferation marker that has an essential function in tumorigenesis due to its positive connection with tumor expansion. Aim: The aim of this study was to evaluate the articulation of Ki‑67 as prognostic
Kailash C Dash   +5 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Immunohistochemical features of ovarian structure at polycystic ovary syndrom depending on the age

open access: yesPatologìâ, 2012
peculiarities of proliferation factors and androgens receptors expression in women with PCOS, depending on age were analyzed. It was revealed that pronounced expression of PCNA, cytokeratin and androgen receptors in stroma and intengification of PCNA ...
I. Yu. Ganzhiy
doaj   +1 more source

Metastatic prolactinoma: case report with immunohistochemical assessment for p53 and Ki-67 antigens [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2005
Pituitary carcinomas are rare neoplasms characterized by craniospinal and/or systemic metastases originated from the pituitary. Their histopathology is frequently indistinguishable from that of benign adenomas. The development of markers that better reflect their behavior is desirable. We present the case of a 47 year-old man with a prolactin-secreting
Crusius, Paulo S.   +9 more
openaire   +4 more sources

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

open access: yesAdvanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro   +25 more
wiley   +1 more source

Variability in the Epithelial Expression of Ki67 and Polarization Characteristics of Collagen in Odontogenic Cysts and Tumours

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To assess the proliferation of epithelium (using the Ki67 index) and the polarization pattern of collagen in selected odontogenic cysts and tumours.
Shakthi Dorai Bhadravathi   +5 more
doaj  

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