Results 1 to 10 of about 170,823 (142)

The intrinsically disorderly story of Ki-67 [PDF]

Open Biology, 2021
Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review some of the current literature regarding the protein.
Lucy Remnant, Natalia Y. Kochanova, Caitlin Reid, Fernanda Cisneros-Soberanis, William C. Earnshaw   +4 more
doaj   +3 more sources

Ki-67 correlations in breast cancer. [PDF]

J Med Life
Brain metastases from breast cancer represent a serious complication, associated with reduced survival and impaired quality of life. Increased patient survival and the limited ability of the blood-brain barrier to be crossed by systemic therapies have led to a rising incidence of these lesions.
Vatavu R, Dumitrescu AM, Stan CI, Haliciu AM, Sava A.   +4 more
europepmc   +3 more sources

Ki-67 staining pattern as a prognostic biomarker for advanced acral melanoma [PDF]

Anais Brasileiros de Dermatologia
Background Acral cutaneous melanoma (ACM) is an aggressive skin cancer, especially when diagnosed in the advanced stage. The Ki-67 is a rapid tool for proliferation rate analysis.
Marcel Arakaki Asato, Isabeli Joaquim Contel, Francisco Alves Moraes Neto, Juliana Polizel Ocanha-Xavier, Nathália Silva Carlos Oliveira, Maxwell A. Fung, Mariangela Esther Alencar Marques, José Cândido Caldeira Xavier-Júnior   +7 more
doaj   +3 more sources

Evaluation of the Proliferation Marker Ki-67 for Improved Risk Stratification of Prostate Cancer Patients Under Active Surveillance [PDF]

Diagnostics
Background/Objectives: Active surveillance (AS) is a viable option for patients with low-risk/low-burden prostate cancer (PCa). Approximately 40–50% of patients will develop disease progression and conversion to active treatment.
Viktoria Schütz, Maresa Rothermel, Adam Kaczorowski, Svenja Dieffenbacher, Sarah Heike Böning, Constantin Schwab, Albrecht Stenzinger, Johannes Huber, Anette Duensing, Markus Hohenfellner, Stefan Duensing   +10 more
doaj   +2 more sources

Ki-67 gene expression [PDF]

Cell Death & Differentiation, 2021
AbstractKi-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are maximally expressed in G2 phase and mitosis. Expression is dependent on two CHR elements and one CDE site in the MKI67 promoter.
Sigrid Uxa, Paola Castillo-Binder, Robin Kohler, Konstanze Stangner, Gerd A. Müller, Kurt Engeland   +5 more
openaire   +2 more sources

Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder

Children, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by behavioral abnormalities such as impairments in social function and deficits in communication. The etiology of autism is unknown in most cases, but many studies have pointed
Khaled Alhosaini, Mushtaq A. Ansari, Ahmed Nadeem, Sabry M. Attia, Saleh A. Bakheet, Laila Y. Al-Ayadhi, Hafiz M. Mahmood, Haneen A. Al-Mazroua, Sheikh F. Ahmad   +8 more
doaj   +1 more source

CD44 Expression in Meningioma and its Correlation with Proliferation Indices [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: CD44 is a cell adhesion molecule assumed to be related to tumour invasion and metastatic ability and is expressed in variety of tumours including meningiomas.
Rasha Ramadan Mostafa, Rasha Ahmed Khairy   +1 more
doaj   +1 more source

Neoplasias astrocitárias e correlação com as proteínas p53 mutada e Ki-67 Astrocytic neoplasms and correlation with mutate p53 and Ki-67 proteins

Arquivos de Neuro-Psiquiatria, 2005
As neoplasias astrocitárias correspondem a 60% dos tumores do sistema nervoso central, sendo o estudo da biologia molecular um importante passo para a compreensão da gênese e comportamento biológico destas doenças.
Gustavo Rassier Isolan, Jurandir Marcondes Ribas Filho, Paola Maria B.S. Isolan, Allan Giovanini, Osvaldo Malafaia, L.I. Dini, Arthur Kummer Jr., Alexandre W. Negrão   +7 more
doaj   +1 more source

Immunohistochemical study of P53 protein expression in different prostate cancer Gleason grading groups

RUDN Journal of Medicine, 2020
Prostate cancer (PC) remains an urgent public health problem, especially in developed countries. The use of immunohistochemical research methods in addition to the morphological classification of prostate adenocarcinomas allows a more accurate diagnosis ...
G. Y. Kudryavtsev, L. V. Kudryavtseva, L. M. Mikhaleva, Y. Y. Kudryavtseva, N. A. Solovyeva, V. A. Osipov, I. I. Babichenko   +6 more
doaj   +1 more source

Hubungan Ekspresi Ki-67 dengan Grading Histopatologi Liposarkoma

Majalah Kedokteran Bandung, 2013
Liposarcoma, a malignant tumor of mesenchymal origin, was one of the most common sarcomas of adults and occurs primarily in the fifth through seventh decades of life. The occurrence in children was rare.
Afiati, Bethy S. Hernowo
doaj   +1 more source