Results 21 to 30 of about 1,258,688 (288)

Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder

Children, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by behavioral abnormalities such as impairments in social function and deficits in communication. The etiology of autism is unknown in most cases, but many studies have pointed
Khaled Alhosaini, Mushtaq A. Ansari, Ahmed Nadeem, Sabry M. Attia, Saleh A. Bakheet, Laila Y. Al-Ayadhi, Hafiz M. Mahmood, Haneen A. Al-Mazroua, Sheikh F. Ahmad   +8 more
doaj   +1 more source

Ki-67 as a Prognostic Biomarker in Invasive Breast Cancer

Cancers, 2021
Simple Summary In breast cancer development, the expression of Ki-67 is strongly associated with cancer proliferation and is a known indicator of prognosis and outcome.
M. Davey, S. Hynes, M. Kerin, N. Miller, A. Lowery   +4 more
semanticscholar   +1 more source

Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring

Modern Pathology, 2022
Ki-67 assessment is a key step in the diagnosis of neuroendocrine neoplasms (NENs) from all anatomic locations. Several challenges exist related to quantifying the Ki-67 proliferation index due to lack of method standardization and inter-reader ...
C. Luchini, L. Pantanowitz, V. Adsay, S. Asa, P. Antonini, I. Girolami, N. Veronese, A. Nottegar, S. Cingarlini, L. Landoni, L. Brosens, A. V. Verschuur, P. Mattiolo, A. Pea, A. Mafficini, M. Milella, M. K. Niazi, Metin Nafi Gurcan, Albino Eccher, I. Cree, A. Scarpa   +20 more
semanticscholar   +1 more source

Habitat radiomics analysis of pet/ct imaging in high-grade serous ovarian cancer: Application to Ki-67 status and progression-free survival

Frontiers in Physiology, 2022
Purpose: We aim to develop and validate PET/ CT image-based radiomics to determine the Ki-67 status of high-grade serous ovarian cancer (HGSOC), in which we use the metabolic subregion evolution to improve the prediction ability of the model. At the same
Xinghao Wang, Chen Xu, Marcin Grzegorzek, Hong-Zan Sun   +3 more
semanticscholar   +1 more source

Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Ki-67 is a nuclear protein present in all proliferating vertebrate cells and is widely used as a marker in clinical cancer histopathology.
K. Mrouj, Nuria Andrés-Sánchez, G. Dubra, Priyanka Singh, M. Sobecki, Dhanvantri Chahar, E. Al Ghoul, A. Aznar, S. Prieto, N. Pirot, F. Bernex, B. Bordignon, Cédric Hassen-Khodja, Martin Villalba, L. Krasinska, D. Fisher   +15 more
semanticscholar   +1 more source

Lung carcinoid tumours: histology and Ki‐67, the eternal rivalry

Histopathology, 2022
WHO classification of Thoracic Tumours defines lung carcinoid tumours (LCTs) as well‐differentiated neuroendocrine neoplasms (NENs) classified in low grade typical (TC) and intermediate grade atypical carcinoids (AC).
G. Centonze, P. Maisonneuve, M. Simbolo, V. Lagano, F. Grillo, A. Fabbri, N. Prinzi, G. Garzone, Martina Filugelli, Carlotta Pardo, A. Mietta, S. Pusceddu, G. Sabella, L. Bercich, A. Mangogna, L. Rolli, S. Grisanti, M. Benvenuti, U. Pastorino, L. Roz, A. Scarpa, A. Berruti, C. Capella, M. Milione   +23 more
semanticscholar   +1 more source

Immunohistochemical study of P53 protein expression in different prostate cancer Gleason grading groups

RUDN Journal of Medicine, 2020
Prostate cancer (PC) remains an urgent public health problem, especially in developed countries. The use of immunohistochemical research methods in addition to the morphological classification of prostate adenocarcinomas allows a more accurate diagnosis ...
G. Y. Kudryavtsev, L. V. Kudryavtseva, L. M. Mikhaleva, Y. Y. Kudryavtseva, N. A. Solovyeva, V. A. Osipov, I. I. Babichenko   +6 more
doaj   +1 more source

CD44 Expression in Meningioma and its Correlation with Proliferation Indices [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: CD44 is a cell adhesion molecule assumed to be related to tumour invasion and metastatic ability and is expressed in variety of tumours including meningiomas.
Rasha Ramadan Mostafa, Rasha Ahmed Khairy   +1 more
doaj   +1 more source

Prognostic role of Ki-67 in glioblastomas excluding contribution from non-neoplastic cells

Scientific Reports, 2021
Survival of glioblastoma patients varies and prognostic markers are important in the clinical setting. With digital pathology and improved immunohistochemical multiplexing becoming a part of daily diagnostics, we investigated the prognostic value of the ...
R. Dahlrot, Julie A. Bangsø, J. K. Petersen, A. M. Rosager, M. Sørensen, G. Reifenberger, S. Hansen, B. Kristensen   +7 more
semanticscholar   +1 more source

Prediction of the Ki-67 marker index in hepatocellular carcinoma based on Dynamic Contrast-Enhanced Ultrasonography with Sonazoid

Insights into Imaging, 2022
Background Ki-67 is widely used as a proliferative and prognostic factor in HCC. This study aimed to analyze the relationship between dynamic contrast-enhanced ultrasonography (DCE-US) parameters and Ki-67 expression.
Zhe Huang, Ping-Ping Zhou, Shan-Shan Li, Kaiyan Li   +3 more
semanticscholar   +1 more source