Results 11 to 20 of about 1,258,688 (288)
The intrinsically disorderly story of Ki-67 [PDF]
Open Biology, 2021 Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review some of the current literature regarding the protein.
Lucy Remnant +4 more
doaj +4 more sources
Cell Death & Differentiation, 2021 Ki-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are maximally expressed in G2 phase and mitosis. Expression is dependent on two CHR
S. Uxa +5 more
semanticscholar +3 more sources
Ki-67 staining pattern as a prognostic biomarker for advanced acral melanoma [PDF]
Anais Brasileiros de DermatologiaBackground Acral cutaneous melanoma (ACM) is an aggressive skin cancer, especially when diagnosed in the advanced stage. The Ki-67 is a rapid tool for proliferation rate analysis.
Marcel Arakaki Asato +7 more
doaj +3 more sources
Prognostic Importance of Ki-67 in Breast Cancer and Its Relationship with Other Prognostic Factors
European Journal of Breast Health, 2019 Objective:The clinical feature of breast cancer is very heterogeneous because of the variable prognostic factors impact its behaviour. The aim of study is to find the prognostic importance of Ki-67 and to analyse the correlation between Ki-67 index and ...
Gül Kanyılmaz +5 more
doaj +2 more sources
Study on the predictive efficacy of Ki-67, ER, and PR levels on the effectiveness of neoadjuvant chemotherapy in breast cancer [PDF]
Frontiers in MedicineAimTo investigate the predictive efficacy of Ki-67 antigen (Ki-67), estrogen receptor (ER), and progesterone receptor (PR) levels on the effectiveness of neoadjuvant chemotherapy (NAC) in breast cancer.MethodsA total of 720 breast cancer patients ...
Lin Lin, Bing Han
doaj +2 more sources
Annals of Oncology, 2021 BACKGROUND Adjuvant abemaciclib combined with endocrine therapy (ET) previously demonstrated clinically meaningful improvement in invasive disease-free survival (IDFS) and distant relapse-free survival (DRFS) in HR+, HER2-, node-positive, high risk early
N. Harbeck +34 more
semanticscholar +1 more source
Cancers, 2023 Simple Summary Cellular proliferation is a central determinant of breast cancer recurrence risk and response to chemotherapy. The discovery of the Ki-67 antibody by Dr.
B. Finkelman +3 more
semanticscholar +1 more source
Ki-67, 21-Gene Recurrence Score, Endocrine Resistance, and Survival in Patients With Breast Cancer
JAMA Network Open, 2023 This cohort study of patients with breast cancer investigates whether Ki-67 expression correlates with the 21-gene recurrence score (RS) and whether high Ki-67 level in patients with a low RS is associated with recurrence and secondary endocrine ...
Janghee Lee +13 more
semanticscholar +1 more source
Journal of Pathology, 2023 The Ki‐67 labeling index (Ki‐67 LI) is a strong prognostic marker in prostate cancer, although its analysis requires cumbersome manual quantification of Ki‐67 immunostaining in 200–500 tumor cells.
N. Blessin +24 more
semanticscholar +1 more source
Physiological functions and roles in cancer of the proliferation marker Ki-67.
Journal of Cell Science, 2022 What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in histopathology? Discovered in 1983, the protein and its regulation of expression and localisation throughout the cell cycle have been well characterised. However,
Nuria Andrés-Sánchez +2 more
semanticscholar +1 more source