Results 41 to 50 of about 1,145,786 (286)

Immunoexpression of Ki-67 in pulmonary hypoplasia

Polish Journal of Pathology, 2013
Adequate pulmonary development at birth is the major determinant of postnatal outcome in the perinatal period. Lung hypoplasia is a poorly defined condition. The aim of this study was to investigate expression of Ki-67 in human fetuses with pulmonary hypoplasia compared to fetuses without pulmonary pathology and malformations of other organs used as ...
M, Dzieniecka, K, Krystosiak, A, Kulig
openaire   +2 more sources

Ki-67 expression in pulmonary tumors [PDF]

Translational Lung Cancer Research, 2016
Ki-67 was introduced more than two decades ago as a measure of the tumor proliferative fraction , in the need for a useful marker that might help clinicians to guide therapy and predict the prognosis of patients with cancer (1). Although several methods have been used to determine the tumor proliferative fraction in the research setting, the only ...
openaire   +2 more sources

Immunohistochemical detection of Hsp90 and Ki-67 in pterygium [PDF]

Diagnostic Pathology, 2013
To examine the immunohistochemical expression of heat shock protein 90 (Hsp90) and Ki-67 protein in human pterygium.Tissues obtained during pterygium surgery of 15 patients who underwent the bare-sclera procedure and 10 normal conjunctivae were studied. All of these pterygia were primary ones. Recurrent pterygia were excluded.
Sebastiá, Roberto, Ventura, Marcelo Palis, Solari, Helena Parente, Antecka, Emilia, Orellana, Maria Eugenia, Burnier, Miguel N   +5 more
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P63 and Ki-67 expression in radicular cyst

Journal of Oral Biology and Craniofacial Research, 2023
The aim of the current study was to identify the expression of P63 and its relation to odontogenic epithelial cell proliferation, severity of the inflammatory infiltrate and size of radicular cysts (RCs).In this retrospective cross-sectional study, 30 cases of paraffin-embedded RCs were randomly selected from the archive.
Mohammed Amjed Alsaegh, Okba Mahmoud, Sudhir Rama Varma, Asok Mathew, Alaa Muayad Altaie, Shengrong Zhu   +5 more
openaire   +3 more sources

Ki-67 labeling index and scoring of stem cell markers in cultured spheroids, in vivo xenografts and implanted spheroids. [PDF]

, 2016
Ki-67 LI (A) was measured in cultured spheroids, in vivo xenografts and implanted spheroids using ki-67 stained histological sections. A semi-quantitative scoring was performed for CD133 (B) nestin (C) and podoplanin (D). Data are shown as means ± SEM, n
Stine Skov Jensen (2889311), Torben A. Kruse (92928), Ann Mari Rosager (2889308), Stine Asferg Petterson (2889314), Bo Halle (2889305), Mark Burton (489123), Mads Thomassen (395200), Bjarne Winther Kristensen (2889317), Charlotte Aaberg-Jessen (2889320), Morten Meyer (467722)   +9 more
core   +1 more source

Ki-67 and the Chromosome Periphery Compartment in Mitosis [PDF]

Trends in Cell Biology, 2017
The chromosome periphery is a complex network of proteins and RNA molecules (many derived from nucleoli) that covers the outer surface of chromosomes and whose function remains mysterious. Although it was first described over 130 years ago, technological advances and the recent discovery that Ki-67 acts as an organiser of this region have allowed the ...
Booth, Daniel G., Earnshaw, William C.
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component [PDF]

, 1996
The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Prognostic value of Ki-67 according to age in patients with triple-negative breast cancer [PDF]

, 2018
Purpose: The prognostic value of Ki-67 in triple-negative breast cancer (TNBC) is yet unclear because the cut-off points employed differ widely and its predictive effect may vary according to age.
V. Zenzola, M. A. Cabezas-Quintario, Correa, Andrea, E. Pérez-Fernández, Y. Izarzugaza, Zenzola, Víctor, Arguelles, Miguel, M. Arguelles, Izarzugaza, Y, Cabezas-Quintario, , María Antonia, García-Foncillas, Jesús, Pérez-Fernández, Elia, J. García-Foncillas, A. Correa   +13 more
core   +1 more source