Results 61 to 70 of about 1,145,786 (286)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Ki-67 expression after muscular injury. [PDF]

, 2015
(A) Immunohistochemistry of Ki-67, (B) Quantitative analysis of Ki-67. (A and B) Ki-67 expression levels in WT and p21KO mice were significantly different at control and 3 days after injury (p < 0.05).
Shinya Hayashi (735018), Takeshi Ueha (119906), Shinsuke Kihara (735022), Noriyuki Kanzaki (735020), Masahiko Haneda (735023), Shuhei Sakata (538523), Masahiro Kurosaka (33052), Takaaki Fujishiro (735019), Shingo Hashimoto (735021), Nobuaki Chinzei (735017), Yoshitada Sakai (119945), Ryosuke Kuroda (735024)   +11 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Avaliação da expressão das metaloproteinases de matriz -1,-2 e -9, presença de miofibroblastos e Ki-67 em ameloblastoma [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014.O ameloblastoma (AM) é um tumor odontogênico benigno que, apesar de apresentar crescimento lento ...
Dutra, Kamile Leonardi
core  

Ki-67 MARKER OF TUMORS PROLIFERATION AS PROGNOSTIC FACTOR AT REGIONAL BREAST CANCER [PDF]

, 2018
Litvinenko О. О., Bugaichov S. G., Litvinenko О. О. Ki-67 MARKER OF TUMORS PROLIFERATION AS PROGNOSTIC FACTOR AT REGIONAL BREAST CANCER. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2018;1(78):94-100. ISSN 0049-6804.
Litvinenko, О. О. (5177738), Bugaichov, S. G. (5177735)   +1 more
core   +1 more source

Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study.

PLoS ONE, 2019
BACKGROUND:Ki-67 is known to be useful in estimating the fraction of proliferation tumor cells in various malignancies. We tried to investigate clinical association of Ki-67 (MIB-1) expression with the oncological outcomes in patients with localized ...
Seok-Soo Byun, Minseung Lee, Sung Kyu Hong, Hakmin Lee   +3 more
doaj   +1 more source

Analysis of human Ki-67 gene promoter and identification of the Sp1 binding sites for Ki-67 transcription

Tumor Biology, 2011
Ki-67 as a cell proliferation marker is tightly associated with maintenance and regulation of the cell division. To understand the mechanism of Ki-67 gene expression and regulation, we first cloned 5'-flanking region and identified the Ki-67 core promoter.
Dong-Sheng, Pei, Guo-Wei, Qian, Hui, Tian, Jie, Mou, Wang, Li, Jun-Nian, Zheng   +5 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Ki-67 expression in astrocytomas [PDF]

, 2019
Objective: To apply immunohistochemical marker Ki-67 and to check it’s expression in various types of Astrocytomas according to their grades. Methodology: The cross sectional study was conducted in Pathology department, Federal Government Services ...
Mushtaq, Huma, Tahir, Muhammad, Gul, Sana, Nawazish, Arfa, Atif, Tehreem   +4 more
core   +2 more sources

Exploratory analyses of the associations between Ki-67 expression, lymph node metastasis, and prognosis in patients with esophageal squamous cell cancer [PDF]

PeerJ
Background The relationships between Ki-67/MKI67 expression, lymph node metastasis (LNM), vascular invasion (VI), and perineural invasion (PI) in esophageal squamous cell cancer (ESCC) remain unclear.
Jianqing Zheng, Bifen Huang, Ying Chen, Bingwei Zeng, Lihua Xiao, Min Wu   +5 more
doaj   +2 more sources