Results 51 to 60 of about 1,145,786 (286)

Prediction of Higher Ki-67 Index in Pituitary Adenomas by Pre- and Intra-Operative Clinical Characteristics

Brain Sciences, 2022
Objective: The Ki-67 index is an indicator of the active proliferation and aggressive behavior of pituitary adenomas (PAs). Appropriate pre- and intra-operatives of the Ki-67 index can help surgeons develop better and more personalized treatment ...
Xuanzhi Wang, Mingwu Li, Xiaofeng Jiang, Fei Wang, Shiying Ling, Chaoshi Niu   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Ki-67 expression in non-cancerous and cancerous cells upon serum starvation. [PDF]

, 2017
Confocal analysis of Ki-67 expression in HDF, HUVEC, MDA-MB-231, HeLa and FaDu cells (analysed over time after serum deprivation), and the relative fluorescence signal quantification (average overlap value percent). (Two-way ANOVA, p-value * P ≤ 0.05; **
Loris Rizzello (2220754), Adrian Steve Joseph (3740326), Andrew Lewis (63672), Lijuan Guan (3740323), Luca Chierico (1800463), Giuseppe Battaglia (288740)   +5 more
core   +1 more source

Prognostic Importance of Ki-67 in Breast Cancer and Its Relationship with Other Prognostic Factors

European Journal of Breast Health, 2019
Objective:The clinical feature of breast cancer is very heterogeneous because of the variable prognostic factors impact its behaviour. The aim of study is to find the prognostic importance of Ki-67 and to analyse the correlation between Ki-67 index and ...
Gül Kanyılmaz, Berrin Benli Yavuz, Meryem Aktan, Mustafa Karaağaç, Mehmet Uyar, Sıddıka Fındık   +5 more
doaj   +1 more source

Ki-67 as a prognostic marker according to breast cancer molecular subtype

Cancer Biology & Medicine, 2016
Objective: Ki-67 plays an important function in cell division, but its exact role is still unknown. Moreover, few works regarding its overall function were published.
Nahed A. Soliman, Shaimaa M. Yussif
doaj   +1 more source

Histochemistry of Ki-67 antigen in ameloblastomas.

Journal of Osaka Dental University, 1999
The proliferative potential of two common histologic variants of ameloblastoma was investigated immunohistochemically using Ki-67 antibody on routinely processed, formalin-fixed, paraffin-embedded sections. Thirty cases of ameloblastomas (15 cases of follicular and 15 cases of plexiform type) were analyzed.
Nagao, Yutaka, Wato, Masahiro, Tanaka, Akio   +2 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Ki-67 proliferációs marker meghatározása emlőrákokban pre- és postoperatív mintákon. Interobserver variabilitás vizsgálata [PDF]

, 2015
A női emlő rákja az egyik vezető halálok a nők körében szerte az egész világon. A mellrák tehető felelőssé az újonnan diagnosztizált ráktípusok 25%-áért, illetve a rák okozta halálesetek 15%-áért.
Tempfli, Raffaella
core  

Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution’s Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer

Breast, 2020
Objectives: The proliferative activity of the Ki-67 index is important in decision-making of adjuvant treatments in early breast cancer. Its reliability can be reduced by inter-observer variability.
Angela Fischer Maranta, Simon Broder, Constanze Fritzsche, Michael Knauer, Beat Thürlimann, Wolfram Jochum, Thomas Ruhstaller   +6 more
doaj   +1 more source