Results 191 to 200 of about 833,353 (279)

Ki Lal ? Ki Lal? in Spanish

Translation Today, 2019
openaire   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Increased HIF-2α and CD105 (endoglin) expression is associated with poor differentiation in pheochromocytomas and paragangliomas. [PDF]

Front Endocrinol (Lausanne)
Günler T, Çordan İ.
europepmc   +1 more source

Terminologie in der KI - KI in der Terminologie

Akten des Symposions Worms, 27.-29.
Drewer, Petra (Ed.), Mayer, Felix (Ed.), Pulitano, Donatella (Ed.)   +2 more
openaire   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Disentangling MRI-derived blood-brain barrier leakage into vascular permeability and surface area. [PDF]

J Cereb Blood Flow Metab
Verstappen D, de Jong JJ, Voorter PH, van Dinther M, van Oostenbrugge RJ, Staals J, Jansen JF, Backes WH.   +7 more
europepmc   +1 more source

To・ki・me・ki

, 1999
openaire   +1 more source

Der St.Galler KI-Kompetenzrahmen als Orientierung für Hochschullehre

Es gibt inzwischen zahlreiche Modelle und Frameworks zu KI-Kompetenzen, die jedoch oft sehr breit angelegt sind und damit nur begrenzt Orientierung für konkrete Bildungsbereiche bieten. Der St.
Bass, Steve, Schallert-Vallaster, Stefanie, Buchner, Josef   +2 more
core  

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Pathological characteristics of cervical lymph node metastases in papillary thyroid carcinoma compared with lung adenocarcinoma. [PDF]

Front Oncol
Shao MX, Niu Y, Wei Y, Zhao ZL, Yu MA.
europepmc   +1 more source