Results 181 to 190 of about 355,596 (243)

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Serum fatty acid profiles across clinicopathologic heterogeneity in breast cancer: an exploratory study. [PDF]

Ther Adv Med Oncol
Mucha PT, Jedrzejewska A, Pakiet A, Jablonska P, Zielinski J, Szczecinska W, Puskulluoglu M, Mika A, Slominska EM, Tomczyk M.   +9 more
europepmc   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Disrupting VE-cadherin Y685 phosphorylation inhibits development of experimental diabetic and prediabetic retinopathy. [PDF]

J Clin Invest
Wang Y, Huang H, Shao F, Eshwaran R, Qin M, Karim N, Ren Y, Dobreva G, Hammes HP, Wieland T, Feng Y.   +10 more
europepmc   +1 more source

Impedance of Nonelectroneutral Solid Electrolyte Interphases With Nanopores: A Theoretical Model

Advanced Science, EarlyView.
Physical modeling reveals that often‐neglected non‐electroneutrality and nanopores in the solid‐electrolyte interphase (SEI) govern the impedance behavior. Under nonreactive conditions, the low‐frequency constant‐phase element (CPE) phenomenon can be attributed to the nonelectroneutral local conditions in the SEI.
Chenkun Li, Jun Huang
wiley   +1 more source

„S ki tudja, ki tévedett”?

Literatura
openaire   +2 more sources

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Habitat analysis and other AI technologies for Ki-67 prediction in hepatocellular carcinoma: a multi-center study. [PDF]

BMC Cancer
Zhao M, Duan C, Zhou X, Gao Y, Diao X, Li F, Zhang J, Sun Z, Zhao R, Wang G.   +9 more
europepmc   +1 more source