Results 51 to 60 of about 715,372 (292)
KI-LOK - Prüfverfahren für KI-basierte Komponenten im Eisenbahnbetrieb
Bestehende Verifikations- und Validierungsmethoden für KI-Systeme stoßen insbesondere bei sicherheitskritischen Anwendungen an ihre Grenzen, da sie die spezifischen Herausforderungen von Black-Box-Modellen und kontinuierlich lernenden Systemen ...
Knoblauch, Dorian +4 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Ki-67 gene knock-down experiment.
, 2017 (A) Confocal analysis of Ki-67 expression in HDF and MDA-MB-231 cells after shRNA knock-down. Bottom part: graph showing the Ki-67 protein quantification.
Loris Rizzello (2220754) +5 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
THE EFFICACY OF ZUCLOPENTHIXOL ACETATE IN PSYCHOTIC PATIENTS
Psychiatry and Clinical Psychopharmacology, 2021 Fourteen psychotic patients, 7 acute manic and 7 exacerbated patients were included in the study to evaluate the clinical effect of zuclopenthixol acetate in viscoleo. Each patient received 50-200mg. of the drug for the first injection. If necessary the
Nesrin DlLBAZ +2 more
doaj
La caricature des démocraties africaines avant et après la baule dans le parachutage et en attendant le vote des bêtes sauvages. [PDF]
Pensées Genre, Penser Autrement, 2022 Cette réflexion porte sur la présence d’éléments de l’histoire politique de l’Afrique francophone dans la fiction romanesque. Par le truchement de la colonisation, l’Afrique occidentale française (AOF) a épousé des valeurs de son ancien maitre ...
Boulkini COULDIATI, Fatimata NOMBRE
doaj
Ki-67 extranuclear distribution.
, 2017 Confocal assays of the distribution and interaction between Ki-67 and BiP (A), COPII (B) and Golgi (C), in HDF (left column) and MDA-MB-231 cells (right column), before and after serum deprivation.
Loris Rizzello (2220754) +5 more
core +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 2021 Das vorliegende Konzept soll interessierte Akteure dabei unterstützen, Forschungs- und Entwicklungsprojekte im Themenfeld KI in der Pflege zu initiieren, zu planen, durchzuführen und zu verstetigen.
Biessmann, Felix +7 more
core +1 more source