Results 181 to 190 of about 202,716 (285)

Comparison between vascular smooth muscle cells isolated from descending thoracic and abdominal aortas of mice in cell function, phenotype features, and gene expression. [PDF]

JVS Vasc Sci
Kamada K, Niu H, Zhang F, Tang GL.
europepmc   +1 more source

Segmentación de células en imágenes KI67

, 2010
La segmentación es un tratamiento digital de imágenes que consiste en la división de una imagen en diferentes zonas, basándose en procedimientos de etiquetado deterministas o estocásticos (pertenecientes o relativos al azar) de contornos y/o regiones de la imagen, y utilizando información de la intensidad y/o información espacial. El objetivo principal
openaire   +2 more sources

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source

Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial. [PDF]

Nat Cancer
Burrell RA, Kumar S, Provenzano E, Pike C, Dayimu A, McIntosh SA, Pitsinis V, King P, Elsberger B, Govindarajulu S, Satherley L, Hadad S, Schmid P, Agrawal A, Akpuluma B, Bell S, Benson JR, Caldas C, Cheeseman D, Chernukhin I, Forouhi P, Gulsen T, Kleidi E, Pinilla K, Qian W, Abraham JE, Carroll JS, Baird RD.   +27 more
europepmc   +1 more source

Ki67 is a promising molecular target in the diagnosis of cancer (review).

Molecular Medicine Reports, 2015
Liantao Li, G. Jiang, Qian Chen, Junnian Zheng   +3 more
semanticscholar   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Correlations between Ki67 expression and uptake of ⁶⁸Ga-FAPI-04 versus ¹⁸F-FDG in different types of tumors: a lesion-based study. [PDF]

Cancer Imaging
Deng J, You D, Zhang C, Peng D, Ma J, Chen Y.   +5 more
europepmc   +1 more source

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

Advanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen, Yi‐Fan Zhou, Xuan Qi, Ya‐Xin Zhao, Tong Fu, Xi Jin, Minhong Shen, Yi‐Zhou Jiang, Zhi‐Ming Shao   +8 more
wiley   +1 more source

Prognostic value of different immunohistopathological patterns and Ki67 proliferation index for Merkel cell carcinoma. [PDF]

Head Face Med
Obermeier KT, Smolka W, Kollmuss M, Wuersching SN, Dewenter I, Poxleiter P, Otto S, Malenova Y, Fegg F, Liokatis P.   +9 more
europepmc   +1 more source

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source