Results 101 to 110 of about 2,352,989 (309)
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
FACTORS INFLUENCING RECOVERY TIME AND HOSPITAL STAY AFTER TRANSURETHRAL RESECTION OF PROSTATE (TURP)
Journal of Gandhara Medical and Dental SciencesOBJECTIVES This study aimed to evaluate the factors influencing recovery time and the length of hospital stay (LHS) following TURP surgery. METHODOLOGY A descriptive study was conducted over 6 months in the Department of Urology at the Institute of
Allah Yar khan +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
KIDNEY CARCINOMA ASSOCIATED WITH XP11.2 TRANSLOCATION / TFE3 (ASPL-TFE3) GENE FUSION
, 2020 We report the case of a 58-year old patient, showing a solid image in the right kidney, who underwent radical nephrectomy that revealed neoplasia, whose pathological study led to the diagnosis of kidney carcinoma associated with Xp11.2 translocation ...
Xp11, Kidney
core
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Cadaveric vs. Live-Donor Kidney Transplants: The Interaction of Institutions and Inequality [PDF]
In 1991, the World Health Assembly approved a set of Guiding Principles which emphasize voluntary donation, non-commercialization and a preference for cadavers over living donors” (World Health Organization).
Mustafa Caglayan, Nejat Anbarci
core +2 more sources
Journal of the Pakistan Medical AssociationObjective: To evaluate short-term outcomes and patient survival among kidney paired donation cases in living donor kidney transplants. Method: The retrospective, observational study was conducted in December 2024 at the Department of Kidney ...
Asad Bashir +5 more
doaj +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease
, 2019 Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst and kidney growth, which is hypothesized to cause loss of functioning renal mass and eventually end-stage kidney disease.
Rahbari-Oskoui, Frederic F. +25 more
core +1 more source