Results 21 to 30 of about 4,267,813 (410)

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

open access: yes, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre   +10 more
core   +2 more sources

Kidney xenotransplantation [PDF]

open access: yesKidney International, 2014
Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process ...
Cowan, PJ, Cooper, DKC, d'Apice, AJF
openaire   +3 more sources

Diabetes Management in Chronic Kidney Disease: A Consensus Report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO)

open access: yesDiabetes Care, 2022
People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent clinical trials support new approaches to treat diabetes and CKD.
I. D. de Boer   +8 more
semanticscholar   +1 more source

Editor's note

open access: yesJournal of Kidney Cancer and VHL, 2014
Dear fellow researchers,Welcome to the first issue of the Journal of Kidney Cancer and VHL (JKCVHL).JKCVHL is an open access journal created to fill the vacuum for a specialized journal to disseminate information on the advances in kidney cancer and VHL ...
Journal of Kidney Cancer and VHL
doaj   +1 more source

Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]

open access: yes, 2019
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core   +2 more sources

Climate change and the kidney [PDF]

open access: yes, 2019
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime   +12 more
core   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

open access: yes, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E.   +3 more
core   +2 more sources

Seasonal mortality trends for hospitalised patients with acute kidney injury across England

open access: yesBMC Nephrology, 2023
Background Incidence of acute kidney injury (AKI) is known to peak in winter months. This is likely influenced by seasonality of commonly associated acute illnesses.
Esther Wong   +6 more
doaj   +1 more source

Kidney age, not kidney disease [PDF]

open access: yesCanadian Medical Association Journal, 2018
KEY POINTS Although a variety of conditions and syndromes may affect the kidneys over either chronic or acute time frames, the term “chronic kidney disease” (CKD) is used to describe a decrease in the filtration ability of the glomerular capillaries in the kidney.
Stevens, Richard J   +10 more
openaire   +6 more sources

A new outlook towards kidney injuries [PDF]

open access: yes, 2012
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core   +2 more sources

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