Results 21 to 30 of about 4,267,813 (410)
Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre +10 more
core +2 more sources
Kidney xenotransplantation [PDF]
Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process ...
Cowan, PJ, Cooper, DKC, d'Apice, AJF
openaire +3 more sources
People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent clinical trials support new approaches to treat diabetes and CKD.
I. D. de Boer +8 more
semanticscholar +1 more source
Dear fellow researchers,Welcome to the first issue of the Journal of Kidney Cancer and VHL (JKCVHL).JKCVHL is an open access journal created to fill the vacuum for a specialized journal to disseminate information on the advances in kidney cancer and VHL ...
Journal of Kidney Cancer and VHL
doaj +1 more source
Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core +2 more sources
Climate change and the kidney [PDF]
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime +12 more
core +1 more source
Emerging key roles for P2X receptors in the kidney [PDF]
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E. +3 more
core +2 more sources
Seasonal mortality trends for hospitalised patients with acute kidney injury across England
Background Incidence of acute kidney injury (AKI) is known to peak in winter months. This is likely influenced by seasonality of commonly associated acute illnesses.
Esther Wong +6 more
doaj +1 more source
Kidney age, not kidney disease [PDF]
KEY POINTS Although a variety of conditions and syndromes may affect the kidneys over either chronic or acute time frames, the term “chronic kidney disease” (CKD) is used to describe a decrease in the filtration ability of the glomerular capillaries in the kidney.
Stevens, Richard J +10 more
openaire +6 more sources
A new outlook towards kidney injuries [PDF]
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core +2 more sources

