Results 51 to 60 of about 2,425,371 (368)
Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study [PDF]
, 2013 Treatment options for autosomal dominant polycystic kidney disease (ADPKD) will likely become available in the near future, hence reliable diagnostic and prognostic biomarkers for the disease are strongly needed.Torres, Vicente E., Poster, D., Andreas D. Kistler, Fabienne Krauer, Kistler Andreas D., Grantham, J.J., Serra, AL, Grantham, Jared J, James E. Bost, Mischak Harald, Bost, J.E., Bost James E., Arlene B Chapman, Chapman, AB, Mrug, M., Wüthrich Rudolf P., Grantham Jared J., Justyna Siwy (103595), Andreas L. Serra (103592), Arlene B. Chapman (103480), Diane Poster (36083), Justyna Siwy, Poster Diane, Bost, James E., Rudolf P. Wüthrich (103623), Krauer, F., Torres, V.E., Mischak, Harald, Serra Andreas L., Wüthrich, Rudolf P, Wüthrich, RP, Kyongtae T. Bae, Bae, KT, James E. Bost (103618), Kistler, AD, Poster, Diane, Siwy, J., Michal Mrug (103606), Grantham, JJ, Bae, Kyongtae T., Serra, Andreas L, Grantham, Jared J., Vicente E. Torres, Torres Vicente E., Mullen, W., Chapman, Arlene B., Bae, Kyongtae T, Fabienne Krauer (103598), Bae, K.T., Bost, James E, Chapman Arlene B., Jared J Grantham, Mullen, W, Vicente E. Torres (103602), Mullen, William, Mrug, M, Andreas D Kistler, Kyongtae T Bae, Siwy, Justyna, Krauer, F, Mischak, H., Mrug, Michal, Wüthrich, Rudolf P., Torres, Vicente E, Andreas L Serra, Harald Mischak (103627), Jared J. Grantham (103610), Krauer, Fabienne, Bost, JE, Rudolf P. Wüthrich, Mrug Michal, Diane Poster, Wuethrich, Rudolf P., Serra, Andreas L., Serra, A.L., William Mullen (103621), William Mullen, Chapman, A.B., Vicente E Torres, Chapman, Arlene B, James E Bost, Mischak, H, Jared J. Grantham, Siwy Justyna, Andreas L. Serra, Kyongtae T. Bae (103614), Wüthrich, R.P., Michal Mrug, Kistler, Andreas D., Poster, D, Krauer Fabienne, Siwy, J, Mullen William, Kistler, A.D., Harald Mischak, Arlene B. Chapman, Torres, VE, Andreas D. Kistler (103588), Bae Kyongtae T., Bae, Kyong Tae, Rudolf P Wüthrich, Kistler, Andreas D +101 morecore +1 more sourceTransferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti +9 morewiley +1 more sourceProtocol and establishment of a Queensland renal biopsy registry in Australia
BMC Nephrology, 2020 Background Renal biopsy is often required to obtain information for diagnosis, management and prognosis of kidney disease that can be broadly classified into acute kidney injury (AKI) and chronic kidney disease (CKD).Joseph Patrick Burke, Manaf Aljishi, Leo Francis, Wendy Hoy, Dakshinamurthy Divi, Roy Cherian, Jeremy Frazier, Glenda Gobe, Pedro Gois, Sridevi Govindarajulu, Sonny Huynh, Shilpanjali Jesudason, George John, Krishan Madhan, Andrew Mallett, Valli Manickam, Clyson Mutatiri, Shu-Kay Ng, Zaw Thet, Peter Trnka, Sree Krishna Venuthurupalli, Dwarakanathan Ranganathan +21 moredoaj +1 more sourceA novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8
, 2012 Background
Nephronophthisis (NPHP) as a cause of cystic kidney disease is the most common genetic cause of progressive renal failure in children and young adults.Morahan, G., Mathew I Bellgard, Roberto A Barrero, Morahan, G, McCooke, J.K., Bellgard, MI, Jacqueline K Phillips, Ding, A., John K McCooke, Appels, R, Grant Morahan, Phillips, J.K., Justyna E Ozimek-Kulik, Phillips, JK, Bellgard, M.I., Barrero, RA, McCooke, JK, Appels, R., Barrero, R.A., Ozimek-Kulik, J.E., Rudi Appels, Alice Ding, Ozimek-Kulik, JE, Ding, A +23 morecore +1 more sourceRationale and design of the Kidney Precision Medicine Project.
, 2021 Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous, and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate a precision-medicine approach to prevention, diagnosis, and treatment.Tuttle, Katherine, Kidney Precision Medicine Project,, El-Achkar, Tarek M, de Boer, Ian H., Troyanskaya, Olga G., Vazquez, Miguel A., Palevsky, Paul M, Gaut, Joseph P., Azeloglu, Evren U, Hodgin, Jeffrey B, Toto, Robert D., Eadon, Michael T, O\u27Toole, John F, Troyanskaya, Olga G, Mariani, Laura H., McClelland, Robyn L., Mooney, Sean D., Brown, Keith, Mariani, Laura H, Bomback, Andrew S, El-Achkar, Tarek M., Barasch, Jonathan M., Schaub, Jennifer A, Sharma, Kumar, Balis, Ulysses G. J., Barisoni, Laura, Waikar, Sushrut S., Lienczewski, Chrysta, Moledina, Dennis G, Alpers, Charles E, Jain, Sanjay, Knight, Richard, Balis, Ulysses G J, Steck, Becky, Dagher, Pierre C, O'Toole, John F, Blank, Kristina N, Laszik, Zoltan G., Alpers, Charles E., Azeloglu, Evren U., Himmelfarb, Jonathan, O'Toole, John F., McClelland, Robyn L, Iyengar, Ravi, Kellum, John A, Kellum, John A., Dighe, Ashveena L, de Boer, Ian H, Wilson, Francis Perry, Kidney Precision Medicine Project, Toto, Robert D, Hodgin, Jeffrey B., Moledina, Dennis G., Waikar, Sushrut S, Williams, Kayleen, Rosas, Sylvia E., Kiryluk, Krzysztof, Kretzler, Matthias, Palevsky, Paul M., Tuttle, Katherine R, Sedor, John R., Sedor, John R, Rosengart, Matthew R, Hacohen, Nir, Poggio, Emilio D, Schaub, Jennifer A., Eadon, Michael T., He, Yongqun, Barasch, Jonathan M, Menez, Steven, Mooney, Sean D, Dagher, Pierre C., Sarwal, Minnie M., Vazquez, Miguel A, Tuttle, Katherine R., Dighe, Ashveena L., Rosengart, Matthew R., Parikh, Chirag R, Sarwal, Minnie M, Blank, Kristina N., Zhang, Kun, Parikh, Chirag R., Bomback, Andrew S., Gaut, Joseph P, Laszik, Zoltan G, Rosas, Sylvia E, Poggio, Emilio D. +86 morecore +1 more sourceTau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido +3 morewiley +1 more sourceSchwannoma of the Kidney [PDF]
Modern Pathology, 2008 Schwannomas of the kidney are rare, with only a few reported cases. We report three additional cases with immunohistochemical analysis. All three tumors were from females (aged 27, 35, and 59 years) and ranged from 4.8 to 8 cm in diameter. All of the patients underwent nephrectomy.GOBBO, Stefano, John N. Eble, Jiaoti Huang, David J. Grignon, Mingsheng Wang, MARTIGNONI, Guido, BRUNELLI, Matteo, Liang Cheng +7 moreopenaire +3 more sources