Results 71 to 80 of about 2,352,989 (309)

Empagliflozin lowers serum uric acid in chronic kidney disease: exploratory analyses from the EMPA-KIDNEY trial [PDF]

Background and hypothesis Hyperuricaemia and gout are common in chronic kidney disease (CKD). We aimed to assess the effects of sodium-glucose co-transporter-2 (SGLT2) inhibition on uric acid (urate) and gout in patients with CKD.
Wanner, Christoph, Emberson, Jonathan, Baigent, Colin, Sammons, Emily, Haynes, Richard, Staplin, Natalie, Zhu, Doreen, Preiss, David, Cherney, David ZI, Mayne, Kaitlin J, Sardell, Rebecca J, EMPA-KIDNEY Collaborative Group, Pontremoli, Roberto, Hauske, Sibylle J., Judge, Parminder K, Landray, Martin J, Green, Jennifer B., Levin, Adeera, Cherney, David Z.I., Herrington, William G., Landray, Martin J., Mayne, Kaitlin J., Judge, Parminder K., Sardell, Rebecca J., Herrington, William G   +24 more
core   +1 more source

Maximum weight cycle packing in directed graphs, with application to kidney exchange programs [PDF]

, 2009
Centralized matching programs have been established in several countries to organize kidney exchanges between incompatible patient-donor pairs. At the heart of these programs are algorithms to solve kidney exchange problems, which can be modelled as ...
Biro, P., Rizzi, R., Manlove, D.F.
core   +1 more source

Protocol and establishment of a Queensland renal biopsy registry in Australia

BMC Nephrology, 2020
Background Renal biopsy is often required to obtain information for diagnosis, management and prognosis of kidney disease that can be broadly classified into acute kidney injury (AKI) and chronic kidney disease (CKD).
Joseph Patrick Burke, Manaf Aljishi, Leo Francis, Wendy Hoy, Dakshinamurthy Divi, Roy Cherian, Jeremy Frazier, Glenda Gobe, Pedro Gois, Sridevi Govindarajulu, Sonny Huynh, Shilpanjali Jesudason, George John, Krishan Madhan, Andrew Mallett, Valli Manickam, Clyson Mutatiri, Shu-Kay Ng, Zaw Thet, Peter Trnka, Sree Krishna Venuthurupalli, Dwarakanathan Ranganathan   +21 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

KDIGO 2022 CLINICAL PRACTICE GUIDELINE FOR THE PREVENTION, DIAGNOSIS, EVALUATION, AND TREATMENT OF HEPATITIS C IN CHRONIC KIDNEY DISEASE

, 2022
The Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease represents a focused update of the 2018 guideline.
Jadoul, Michel, Goldberg, David, Martin, Paul, Kidney Disease: Improving Global Outcomes (KDIGO) Hepatitis C Work Group   +3 more
core   +1 more source

Comparative outcomes of separate versus pantaloon anastomosis in two renal artery living donor kidney transplantation: a retrospective cohort study

Clinical Transplantation and Research
Background : The optimal surgical approach for managing multiple renal arteries in living donor kidney transplantation remains unclear. This study compared outcomes between separate anastomoses (SA) and pantaloon anastomosis (PA).
Asad Bashir, Zia Ul Haq Akram, Nasrum Minallah, Fiaz Ahmad Touqeer, Ali Asad, Mariam Asad, Zaghum Shazad, Muhammad Faheem Aslam, Sehrish Tehreem, Ammar Yousaf   +9 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Vitamin D and endothelial function in chronic kidney disease [PDF]

, 2014
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial.

BACKGROUND: Sodium-glucose co-transporter-2 (SGLT2) inhibitors reduce progression of chronic kidney disease and the risk of cardiovascular morbidity and mortality in a wide range of patients.
Tuttle (EMPA-KIDNEY Collaborative Group), Katherine, EMPA-KIDNEY Collaborative Group,   +1 more
core   +2 more sources