Results 51 to 60 of about 1,048,945 (331)

Robot-assisted laparoendoscopic single-site surgery for the simultaneous management of multiple urinary tract calculi: a case report and experience sharing

open access: yesBMC Urology, 2019
Background Urolithiasis is a clinically common benign disease in urology. Surgical treatments that are widely used in urolithiasis are percutaneous nephrolithotomy, rigid/flexible ureteroscopy, laparoscopic surgery, and endoscopic combined intrarenal ...
Fan Zhang   +10 more
doaj   +1 more source

Risk factors for systemic inflammatory response syndrome after endoscopic lithotripsy for upper urinary calculi

open access: yesBMC Urology, 2023
Background To explore the risk factors for systemic inflammatory response syndrome (SIRS) after endoscopic lithotripsy for upper urinary calculi. Methods This retrospective study included patients with upper urinary calculi who underwent endoscopic ...
Siming Ye   +3 more
doaj   +1 more source

Focused Ultrasound to Expel Calculi From the Kidney [PDF]

open access: yesJournal of Urology, 2012
A persistent stone burden after renal stone treatment may result in future patient morbidity and potentially lead to additional surgery. This problem is particularly common after treatment of lower pole stones. We describe a potential noninvasive therapeutic option using ultrasound waves to create a force sufficient to aid in stone fragment expulsion ...
Jonathan D. Harper   +8 more
openaire   +3 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Extra-large renal calculi removal using single puncture percutaneous nephrolithotomy

open access: yesUrology Annals, 2019
With the ever-increasing use of ultrasonography and X rays, renal calculi are being detected while still small thus large renal calculi are becoming less common. Percutaneous nephrolithotomy (PCNL) is a gold standard for the treatment of renal calculi >2
Parag M Gavande, Harsha P Gavande
doaj   +1 more source

Present Role of Gray Scale Ultrasound Combined with Doppler in the Evaluation of Ureteric Calculi: Correlation with CT-Scan [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2016
Introduction: One of the commonest causes for acute flank pain is ureteric calculi. Presently imaging modalities available in the evaluation of ureteric calculi include plain radiography, ultrasound, intravenous urography, noncontrast computed ...
Deepu Remakanthan   +3 more
doaj   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

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