Results 81 to 90 of about 29,081 (306)

Retinal micro-vascular and aortic macro-vascular changes in postmenopausal women with primary hyperparathyroidism [PDF]

, 2018
Aim of the study was to evaluate the micro and macro-vascular changes in patients with primary hyperparathyroidism (PHPT) compared to controls. 30 postmenopausal PHPT women (15 hypertensive and 15 normotensive) and 30 normotensive controls underwent ...
Biamonte, Federica, Cipriani, Cristiana, Colangelo, Luciano, Curione, Mario, Minisola, Salvatore, Parravano, Mariacristina, Pepe, Jessica, Tedeschi, Massimiliano, Varano, Monica   +8 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Loss of Renal Function After Retrograde Ureteral Placement of an Allium Stent for Severe Ureteral Stricture [PDF]

, 2018
Background: Ureteral strictures are a recurrent chronic condition that leads to severe side effects and poor quality of life. Management of ureteral stricture is a great challenge for urologists and no specific guidelines exist ...
Alpi, Giorgio, Ciccariello, Mauro, D'Eramo, Giuseppe, Gentilucci, Alessandro, Lai, Silvia, Maggi, Martina, Polese, Milena, Ricciuti, Gian Piero, Salciccia, Stefano, Sciarra, Alessandro, Shahabadi, Houssain   +10 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Staghorn calculi and xanthogranulomatous pyelonephritis associated with transitional cell carcinoma

Urological Science, 2015
Untreated staghorn calculi can cause xanthogranulomatous pyelonephritis (XGP), diminished renal function, and renal malignancy. Squamous cell carcinoma (SCC) of the upper urinary tract is associated with kidney stones and chronic infection, but their ...
Chao-Wei Tseng, Wei-Nung Jim Chen, Guang-Dar Juang, Thomas I-Sheng Hwang   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Crossed Fused Ectopic Kidney with Stone Disease and Bifid Renal Pelvis: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Crossed fused ectopic kidney is a rare congenital anomaly wherein the kidneys are present on the same side due to fusion. It is a rare disease that may remain undiagnosed throughout life.
Vikram Satav, Ashish Gavade, Vilas Sabale, Sunil Mhaske, Shashikant Asabe   +4 more
doaj   +1 more source

High Zn content of Randall's plaque: A μ-X-ray fluorescence investigation [PDF]

, 2011
Kidney stone disease, or nephrolithiasis, is a common ailment. Among the different risk factors usually associated with nephrolithiasis are dehydration, metabolic defects (especially with regard to calcium and oxalate).
Albouy, Pierre-Antoine, Bazin, Dominique, Carpentier, Xavier, Combes, Christèle, Daudon, Michel, Foy, Eddy, Mazouyes, Aurélie, Rouzière, Stephan   +7 more
core   +2 more sources

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

In vitro analysis of urinary stone composition in dual-energy computed tomography [PDF]

, 2018
Purpose: Dual energy computed tomography (DECT) is a new method of computed tomography (CT) imaging, allowing the assessment of not only the object's morphology, but also its composition.
Chrzan, Robert, Gawlas, Wojciech, Stępień, Monika   +2 more
core   +1 more source