Results 171 to 180 of about 1,911,748 (355)
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao+8 more
wiley +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Kidney transplantation is the treatment of choice for many individuals with end stage renal disease (ESRD), as transplantation is reported to offer a greater quality of life than renal dialysis.
Addington-Hall, Julia+4 more
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II. Removal by Abdominal Section of a Large Sarcoma of the Kidney, Which had Undergone Extensive Cystic Degeneration. Recovery from the Operation. Rapid Recurrence of the Disease [PDF]
C. T. CULLINGWORTH, W. Bruce Clarke
openalex +1 more source
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
On the Nature and Treatment of Stomach and Renal Diseases; being an Inquiry into the Connexion of Diabetes, Calculus, and other Affections of the Kidney and Bladder, with Indigestion [PDF]
openalex +1 more source
THE RELATION OF ASCITES TO DISEASES OF THE KIDNEYS, AND PARACENTESIS ABDOMINALIS AS A REMEDY. [PDF]
W. F. McNUTT
openalex +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
DECAPSULATION OF THE KIDNEYS FOR CHRONIC BRIGHT'S DISEASE [PDF]
George M. Edebohls
openalex +1 more source