Results 181 to 190 of about 1,749,999 (379)

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

open access: yesAdvanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma   +10 more
wiley   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

The Energy Cost of the Excretion of Urine [PDF]

open access: yes, 1931
The energy consumption of the kidney has been estimated by a number of experimenters and by different methods; and the values obtained are all of the same order of magnitude.
Borsook, Henry, Winegarden, Howard M.
core  

Living Microalgae‐Based Magnetic Microrobots for Calcium Overload and Photodynamic Synergetic Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A magnetic microrobot fabricated by Spirulina platensis is proposed to accumulate in tumor regions and generate in situ high calcium concentration and sufficient oxygen. These characteristics of the microrobot present a strategy for triggering calcium overload therapy and chlorophyll‐mediated photodynamic therapy, and such combination resulted in a ...
Shuai Jiang   +12 more
wiley   +1 more source

Engineered In Vitro Multi‐Cell Type Ventricle Model Generates Long‐Term Pulsatile Flow and Modulates Cardiac Output in Response to Cardioactive Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an innovative in vitro model of a human left ventricle using biofunctionalized PDMS membranes and human iPSC‐derived cardiomyocytes. The engineered ventricle demonstrates stable, long‐term pulsatile flow, and physiological responses to cardioactive drugs.
Christoph Kuckelkorn   +6 more
wiley   +1 more source

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

open access: yesBMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He   +5 more
doaj   +1 more source

A CNN Approach to Polygenic Risk Prediction of Kidney Stone Formation [PDF]

open access: yesarXiv
Kidney stones are a common and debilitating health issue, and genetic factors play a crucial role in determining susceptibility. While Genome-Wide Association Studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs) linked to kidney stone risk, translating these findings into effective clinical tools remains a challenge.
arxiv  

Deprivation and Disease in Early Twentieth-Century America [PDF]

open access: yes
This paper explores how early life exposure to poverty and want adversely affects later life health outcomes. In particular, it examines how exposure to crowded housing conditions and impure drinking water undermines long-term health prospects and ...
Karen Clay, Werner Troesken
core  

Home - About - Disclaimer - Privacy