Results 241 to 250 of about 1,911,748 (355)
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
THE KIDNEY AS A SOURCE OF BLOOD AMMONIA IN PATIENTS WITH LIVER DISEASE: THE EFFECT OF ACETAZOLAMIDE *† [PDF]
Edward E. Owen+3 more
openalex +1 more source
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni+8 more
wiley +1 more source
OBSERVATIONS ON THE ACIDIFYING CAPACITY OF THE EXPERIMENTALLY DISEASED KIDNEY IN THE DOG* [PDF]
Peter A. F. Morrin+3 more
openalex +1 more source
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz+2 more
wiley +1 more source
Community Water Trihalomethanes and Chronic Kidney Disease.
Medgyesi DN+12 more
europepmc +1 more source
Prognosis of kidney disease in children. Rosenmoller (Arch. f. Kinderheil., 1928, Bd. 84)
openalex +2 more sources
Myotonic dystrophy and polycystic disease of the kidneys. [PDF]
Alan E H Emery+2 more
openalex +1 more source
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma+8 more
wiley +1 more source