Results 281 to 290 of about 1,911,748 (355)

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Machine learning models to predict osteoporosis in patients with chronic kidney disease stage 3-5 and end-stage kidney disease. [PDF]

Sci Rep
Hsu CT, Huang CY, Chen CH, Deng YL, Lin SY, Wu MJ.   +5 more
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

A J-shaped relationship between hemoglobin levels and chronic kidney disease. [PDF]

Sci Rep
Yin R, Li M, Liu C, Pu X, Yi W, Wu Y.
europepmc   +1 more source

Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling

Advanced Materials, EarlyView.
3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli, Aybike Kocatürkmen, Oommen P. Oommen, Oommen P. Varghese   +3 more
wiley   +1 more source

Hereditary kidney disease with auditory abnormalities: analysis of mutations and clinical phenotypes. [PDF]

BMC Med Genomics
Bi J, Guo W, Ji P, Xie Y.
europepmc   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Endothelial dysfunction in chronic kidney disease: a clinical perspective. [PDF]

Am J Physiol Heart Circ Physiol
Cho ME, Brunt VE, Shiu YT, Bunsawat K.
europepmc   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source

Sonodynamic and Bioorthogonal Sonocatalytic Thrombotic Therapy Based on AIE Cationic Tetranuclear Ir(III) Complex Nanoplatform Guided by NIR‐Chemiluminescence Imaging

Advanced Materials, EarlyView.
AIE‐active tetranuclear Ir(III) complex Ir‐4 as a sonosensitizer/sonocatalyst is formulated into a nanoplatform with an H2S donor. Ir‐4@S‐R NPs achieves combined endogenous NIR chemiluminescence imaging, sonodynamic therapy and release of H2S in situ by a bioorthogonal sonocatalytic reaction in vivo, achieving safe thrombolysis and anti‐inflammatory ...
Zihan Wu, Liping Zhang, Ziwei Wang, Shengnan Liu, Qiaohua Zhang, Chunguang Shi, Yachao Wang, Gelin Xu, Dongxia Zhu, Martin R. Bryce, Lijie Ren, Ben Zhong Tang   +11 more
wiley   +1 more source