Results 21 to 30 of about 2,023,116 (304)

Renal hemosiderosis presenting with acute kidney Injury and macroscopic hematuria in Immunoglobulin A nephropathy: a case report

BMC Nephrology, 2021
Background Macroscopic hematuria-associated acute kidney injury (AKI) is a well-known complication of immunoglobulin A (IgA) nephropathy. In such cases, intratubular obstruction by red blood cell (RBC) casts and acute tubular necrosis are mainly observed
Shinya Taguchi, Sumi Hidaka, Mitsuru Yanai, Kunihiro Ishioka, Kenji Matsui, Yasuhiro Mochida, Hidekazu Moriya, Takayasu Ohtake, Shuzo Kobayashi   +8 more
doaj   +1 more source

Association Between Syndecan-1, Fluid Overload, and Progressive Acute Kidney Injury After Adult Cardiac Surgery

Frontiers in Medicine, 2021
Background: Acute kidney injury (AKI) is a common complication after cardiac surgery and the prognosis of AKI worsens with the increase in AKI severity. Syndecan-1(SDC-1) is a biomarker of endothelial glycocalyx degradation.
Jiarui Xu, Jiarui Xu, Wuhua Jiang, Wuhua Jiang, Yang Li, Yang Li, Haoxuan Li, Haoxuan Li, Xuemei Geng, Xuemei Geng, Xin Chen, Xin Chen, Jiachang Hu, Jiachang Hu, Bo Shen, Bo Shen, Yimei Wang, Yimei Wang, Yi Fang, Yi Fang, Chunsheng Wang, Zhe Luo, Guowei Tu, Jie Hu, Xiaoqiang Ding, Xiaoqiang Ding, Xiaoqiang Ding, Jie Teng, Jie Teng, Jie Teng, Xialian Xu, Xialian Xu   +31 more
doaj   +1 more source

Climate change and the kidney [PDF]

, 2019
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime, Diaz, Henry F., Garcia, Gabriela, Hernando, Ana Andres, Johnson, Richard J., Lanaspa, Miguel A., Lemery, Jay, Newman, Lee S., Rodriguez-Iturbe, Bernardo, Roncal-Jimenez, Carlos A., Sato, Yuka, Sánchez-Lozada, Laura G., Tolan, Dean R.   +12 more
core   +1 more source

Chronic kidney disease [PDF]

The Lancet, 2021
Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle adjustments ...
Kalantar-Zadeh, Kamyar, Jafar, Tazeen H, Nitsch, Dorothea, Neuen, Brendon L, Perkovic, Vlado   +4 more
openaire   +4 more sources

Chronic Kidney Disease

Disease-a-Month, 2015
In his review article in the March 2015 edition ofCME, Prof. A M Meyers refers to chronic kidneydisease as 'an important disease group that threatenshealth'. I fully concur with this observation andwish to go a step further and assert that kidneydisease, together with other related non-communicable diseases(NCDs), poses not only a threat to health but ...
Catherine E. Langston, Adam E. Eatroff
  +8 more sources

Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup [PDF]

, 2017
Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice.
A Dewitte, A Ishani, A Ishani, A Morden, AB Pai, AG Schneider, AJ Lewington, Alexander Zarbock, AM Patel, AS Levey, Azra Bihorac, B Rodriguez-Iturbe, B Rodriguez-Iturbe, BB Newsome, BJ Philips, BS Moffett, C Mudumbai, C Ronco, C Vinsonneau, C-T Chao, CC Shiao, CJ Kirwan, Claudio Ronco, CM Bell, CM Horkan, CY Hsu, CY Hsu, D Korenkevych, D Ponce, D Schnell, David Bittleman, Dinna Cruz, DM Thomas, DW Brown, E Wang, EA Coleman, EA Hoste, EA Hoste, EA Hoste, ED Siew, ED Siew, ED Siew, ED Siew, ED Siew, Edward D. Siew, Eric Hoste, ES Kirkendall, Etienne Macedo, F Lapi, FG Brivet, GV do Nascimento, H de Geus, H Graf, H Schiffl, HL Smets, I Benz-de Bretagne, I Koulouridis, I Nachtigall, ID Bucaloiu, IH Khan, J Bouchard, J Bouchard, J Herrera, J Herrera, J Kaufman, J Zavada, JA Kellum, JA Kellum, JA Kellum, JA Kellum, Jay Koyner, JF Platt, JJ Dixon, JO Friedrich, John A. Kellum, JP Bosch, JP Nicholson, JR Brown, JR Brown, JR Prowle, JW Pickering, JW Pickering, K Doi, K Solez, Kathleen D. Liu, KD Liu, KR Pechman, L Cox, LA Tomlinson, Lakhmir S. Chawla, LJ Hickson, LS Chawla, LS Chawla, LS Chawla, LS Chawla, LS Chawla, Lui Forni, M Carlier, M Darmon, M Heung, M Heung, M Huber, M James, M Jun, M Monseu, M Xie, MA Onuigbo, Marlies Ostermann, MB Kwong, ME Matheny, Mitchell Rosner, Mitra Nadim, MM Chrymko, MM Sood, MT James, MT James, N Pannu, N Srisawat, Neesh Pannu, P Sharma, PA Duran, Patrick Murray, Paul M. Palevsky, PH van der Voort, PK Tao Li, PM Palevsky, PM Palevsky, R Cartin-Ceba, R Chu, R Jelliffe, R Rivosecchi, R Wald, R Wald, RA Parker, Ravindra Mehta, Rinaldo Bellomo, RK Basu, RL Amdur, RL Mehta, Robert L. Fitzgerald, Ron Wald, S Chen, S Ftouh, S Ninet, S Perinel, S Uchino, S Uchino, SA Silver, Sandra L. Kane-Gill, SC Gautam, Sean M. Bagshaw, SG Coca, SG Coca, SL Goldstein, SL Goldstein, SL Hu, SL Kane-Gill, SM Bagshaw, SM Handler, SM Jang, SM Lee, SM Moran, SP Kelleher, Stuart L. Goldstein, TJ Pianta, TY Wu, VC Wu, VC Wu, W Picard, Z Harel, ZH Endre, ZH Endre, ZL Cox, Zoltan Endre   +173 more
core   +2 more sources

Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases

Renal Failure, 2018
Background: Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells ...
Yuanyuan Li, Xueyong Liu, Wei Wang, Shaohua Wang, Jianchun Zhang, Song Jiang, Yang Wang, Liping Li, Jinghua Li, Youkang Zhang, Haichang Huang   +10 more
doaj   +1 more source

Pyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury

Cell Death and Disease, 2023
An important pathophysiological process of acute kidney injury (AKI) is mitochondrial fragmentation in renal tubular epithelial cells, which leads to cell death.
Wenjia Xie, Qingyun He, Yan Zhang, Xinxin Xu, Ping Wen, Hongdi Cao, Yang Zhou, Jing Luo, Junwei Yang, Lei Jiang   +9 more
doaj   +1 more source

Molecular Mechanisms of Kidney Injury and Repair in Arterial Hypertension [PDF]

, 2019
The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and arterial hypertension, are key factors contributing to the development and progression of chronic kidney disease. Arterial hypertension is induced and maintained by
Eckardt, Kai-Uwe, Sievers, Laura Katharina   +1 more
core   +2 more sources

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou, Ariela Benigni, B Jonsson, Bernd Mayer, C Delles, C Weyer, C Zoja, Carlamaria Zoja, CD Wenger, CL Oltman, CS Fox, D Theodorescu, Ferdinand H. Bahlmann, H Mischak, H Mischak, Harald Mischak, J Drube, J Toblli, JO Deguchi, Joachim Jankowski, Julie Klein, Justyna Siwy, K Voros, Karin Jandeleit-Dahm, M Hashemi, M Haubitz, N Ahmed, N Verzijl, ND Rawlings, P Zurbig, Paul Perco, PJ Talmud, PR Cutillas, R Rouse, Robert Stevens, S Andersen, S Wild, SA Varghese, Sophia Kossida, T Nakagawa, TW Kurtz, Wiliam Mullen, Y Benjamini, Y Igarashi   +43 more
core   +13 more sources