Results 21 to 30 of about 1,235,496 (168)

Association Between Syndecan-1, Fluid Overload, and Progressive Acute Kidney Injury After Adult Cardiac Surgery

Frontiers in Medicine, 2021
Background: Acute kidney injury (AKI) is a common complication after cardiac surgery and the prognosis of AKI worsens with the increase in AKI severity. Syndecan-1(SDC-1) is a biomarker of endothelial glycocalyx degradation.
Jiarui Xu, Jiarui Xu, Wuhua Jiang, Wuhua Jiang, Yang Li, Yang Li, Haoxuan Li, Haoxuan Li, Xuemei Geng, Xuemei Geng, Xin Chen, Xin Chen, Jiachang Hu, Jiachang Hu, Bo Shen, Bo Shen, Yimei Wang, Yimei Wang, Yi Fang, Yi Fang, Chunsheng Wang, Zhe Luo, Guowei Tu, Jie Hu, Xiaoqiang Ding, Xiaoqiang Ding, Xiaoqiang Ding, Jie Teng, Jie Teng, Jie Teng, Xialian Xu, Xialian Xu   +31 more
doaj   +1 more source

Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases

Renal Failure, 2018
Background: Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells ...
Yuanyuan Li, Xueyong Liu, Wei Wang, Shaohua Wang, Jianchun Zhang, Song Jiang, Yang Wang, Liping Li, Jinghua Li, Youkang Zhang, Haichang Huang   +10 more
doaj   +1 more source

Pyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury

Cell Death and Disease, 2023
An important pathophysiological process of acute kidney injury (AKI) is mitochondrial fragmentation in renal tubular epithelial cells, which leads to cell death.
Wenjia Xie, Qingyun He, Yan Zhang, Xinxin Xu, Ping Wen, Hongdi Cao, Yang Zhou, Jing Luo, Junwei Yang, Lei Jiang   +9 more
doaj   +1 more source

The Association of Syndecan-1, Hypercoagulable State and Thrombosis and in Patients With Nephrotic Syndrome

Clinical and Applied Thrombosis/Hemostasis, 2021
The aim of this study is to investigate whether Syndecan-1 (SDC-1), an indicator of endothelial glycocalyx injury, would increase the risk of hypercoagulable state and thrombosis in patients with nephrotic syndrome (NS).
Xin Chen, Xuemei Geng, Shi Jin, Jiarui Xu, Man Guo, Daoqi Shen, Xiaoqiang Ding, Hong Liu, Xialian Xu   +8 more
doaj   +1 more source

Effect of continuous hemodiafiltration using an AN69ST membrane in patients with sepsis

Renal Replacement Therapy, 2017
Background Sepsis is a systemic inflammatory response syndrome caused by infectious disease. Severe sepsis and septic shock are extremely serious conditions with poor prognoses.
Akihito Tanaka, Daijo Inaguma, Tomoaki Nakamura, Yu Watanabe, Eri Ito, Naoki Kamegai, Hiroya Shimogushi, Minako Murata, Hibiki Shinjo, Kiyomi Koike, Yasuhiro Otsuka, Asami Takeda   +11 more
doaj   +1 more source

CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair

Cell Death and Disease, 2021
Impaired energy metabolism in proximal tubular epithelial cells (PTECs) is strongly associated with various kidney diseases. Here, we characterized proximal tubular phenotype alternations during kidney injury and repair in a mouse model of folic acid ...
Qi Yuan, Yunhui Lv, Hao Ding, Qingqing Ke, Caifeng Shi, Jing Luo, Lei Jiang, Junwei Yang, Yang Zhou   +8 more
doaj   +1 more source

Cilostazol-induced acute tubulointerstitial nephritis accompanied by IgA nephropathy: a case report

BMC Nephrology, 2018
Background Cilostazol is an antiplatelet drug that is widely prescribed for the prevention of secondary stroke. Adverse reactions to cilostazol include headaches, palpitations, and diarrhea. Little is known about the nephrotoxicity of cilostazol, such as
Hisato Shima, Manabu Tashiro, Satoshi Yamada, Motokazu Matsuura, Kazuyoshi Okada, Toshio Doi, Jun Minakuchi, Shu Kawashima   +7 more
doaj   +1 more source

High prevalence of peripheral arterial disease (PAD) in incident hemodialysis patients: screening by ankle-brachial index (ABI) and skin perfusion pressure (SPP) measurement

Renal Replacement Therapy, 2018
Background Peripheral arterial disease (PAD) has much impact on mortality in hemodialysis (HD) patients. Ankle-brachial index (ABI) and skin perfusion pressure (SPP) are useful tools to detect PAD in HD patients.
Kunihiro Ishioka, Takayasu Ohtake, Hidekazu Moriya, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Sumi Hidaka, Shuzo Kobayashi   +7 more
doaj   +1 more source

Systemic sclerosis complicated with renal thrombotic microangiopathy: a case report and literature review

BMC Nephrology, 2022
Background Systemic sclerosis (SSc) may overlap with other connective tissue diseases, which is named overlap syndrome. Scleroderma renal crisis (SRC) is a rare but severe complication of SSc.
Weiwei Kong, Yaomin Wang, Huiping Wang, Qin Zhou, Jianghua Chen, Fei Han   +5 more
doaj   +1 more source

Intradialytic hypotension is an important risk factor for critical limb ischemia in patients on hemodialysis

BMC Nephrology, 2019
Background Critical limb ischemia (CLI) and intradialytic hypotension (IDH) are common complications in patients on hemodialysis (HD). However, limited data are available on whether IDH is related to CLI in these patients.
Ryo Matsuura, Sumi Hidaka, Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Kyoko Maesato, Machiko Oka, Hidekazu Moriya, Shuzo Kobayashi   +8 more
doaj   +1 more source