Results 31 to 40 of about 1,235,496 (168)

Acquired aplastic anemia complicated with anti-glomerular basement membrane disease successfully treated with immunosuppressive therapy: a case report

open access: yesBMC Nephrology, 2022
Background Aplastic anemia (AA) is a rare but fatal disorder characterized by pancytopenia due to bone marrow hypoplasia. Anti-glomerular basement membrane disease (anti-GBM disease) is an immune complex small-vessel vasculitis that presents as rapidly ...
Kenji Matsui   +8 more
doaj   +1 more source

Long-term treatment of evocalcet in hemodialysis patients with secondary hyperparathyroidism: a five-year prospective cohort study in 147 Japanese patients

open access: yesRenal Replacement Therapy
Background Cinacalcet hydrochloride (cinacalcet), an oral calcimimetics for secondary hyperparathyroidism (SHPT), has been widely used worldwide. In contrast, evocalcet, an improved derivative of cinacalcet, was approved only in Japan in 2018 and has not
Nobuo Nagano   +9 more
doaj   +1 more source

Polycystic Kidney Disease [PDF]

open access: yesAnnual Review of Medicine, 2009
A number of inherited disorders result in renal cyst development. The most common form, autosomal dominant polycystic kidney disease (ADPKD), is a disorder most often diagnosed in adults and caused by mutation in PKD1 or PKD2. The PKD1 protein, polycystin-1, is a large receptor-like protein, whereas polycystin-2 is a transient receptor potential ...
Peter C, Harris, Vicente E, Torres
openaire   +2 more sources

Age-stratified association between hyperpolypharmacy (≥ 10 medications) and mortality in patients undergoing maintenance hemodialysis: a 3-year single-center study

open access: yesRenal Replacement Therapy
Background Patients undergoing maintenance hemodialysis frequently experience polypharmacy because of multiple comorbidities. Although polypharmacy has been linked to increased mortality in the general elderly population, its impact on survival may ...
Nobuo Nagano   +7 more
doaj   +1 more source

Sucroferric oxyhydroxide decreases serum phosphorus level and fibroblast growth factor 23 and improves renal anemia in hemodialysis patients

open access: yesBMC Research Notes, 2018
Objective Sucroferric oxyhydroxide, a novel iron-based phosphate-binder, has been shown to have beneficial effects in lowering serum phosphorus levels and improving renal anemia in clinical studies.
Hisato Shima   +4 more
doaj   +1 more source

Elevated circulating growth differentiation factor 15 is related to decreased heart rate variability in chronic kidney disease patients

open access: yesRenal Failure, 2021
Background Growth differentiation factor 15(GDF15) is a distant member of the superfamily of the transforming growth factor beta (TGF-β). It has been established that increased GDF15 levels are associated with an increased risk of cardiovascular disease.
Lulu Wang   +7 more
doaj   +1 more source

The risk factors and predictive model for cardiac valve calcification in patients on maintenance peritoneal dialysis: a single-center retrospective study

open access: yesRenal Failure, 2023
Background Cardiovascular calcification includes cardiac valve calcification (CVC) and vascular calcification. We aimed to analyze risk factors for CVC, and construct a predictive model in maintenance peritoneal dialysis (MPD) patients.Methods We ...
Yuxi Wang   +7 more
doaj   +1 more source

Impact of parathyroidectomy on left ventricular function in end stage renal disease patients

open access: yesBMC Nephrology, 2020
Background Secondary hyperparathyroidism (SHPT) is a common complication in end-stage renal disease (ESRD) patients, and parathyroidectomy (PTX) is an effective treatment intervention of SHPT.
Shaohua Chen   +8 more
doaj   +1 more source

Orphan Kidney Diseases [PDF]

open access: yesNephron Clinical Practice, 2012
Rare kidney diseases are a unique subset of renal disorders that are often termed ‘orphan’ as a result of a multitude of reasons: the small number of patients with the consequent lack of well-defined natural history and course of many of these diseases, limited awareness among the medical community, and finally the significant cost of developing novel ...
openaire   +2 more sources

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