The aim of this study is to investigate whether Syndecan-1 (SDC-1), an indicator of endothelial glycocalyx injury, would increase the risk of hypercoagulable state and thrombosis in patients with nephrotic syndrome (NS).
Xin Chen +8 more
doaj +1 more source
Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G. +6 more
core +1 more source
Dose of colistin. a work in progress? [PDF]
We thank Rashid and colleagues [1] and Honoré and colleagues [2] for their comments regarding our article on risk factors for acute kidney injury in pa- tients receiving colistin or other nephrotoxic antimi- crobials [3].
Antonelli, M. +3 more
core +1 more source
Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R. +7 more
core +1 more source
Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou +43 more
core +7 more sources
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna +11 more
core +5 more sources
Effect of continuous hemodiafiltration using an AN69ST membrane in patients with sepsis
Background Sepsis is a systemic inflammatory response syndrome caused by infectious disease. Severe sepsis and septic shock are extremely serious conditions with poor prognoses.
Akihito Tanaka +11 more
doaj +1 more source
Phenotype standardization for drug-induced kidney disease. [PDF]
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda +8 more
core +2 more sources
Cilostazol-induced acute tubulointerstitial nephritis accompanied by IgA nephropathy: a case report
Background Cilostazol is an antiplatelet drug that is widely prescribed for the prevention of secondary stroke. Adverse reactions to cilostazol include headaches, palpitations, and diarrhea. Little is known about the nephrotoxicity of cilostazol, such as
Hisato Shima +7 more
doaj +1 more source
CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair
Impaired energy metabolism in proximal tubular epithelial cells (PTECs) is strongly associated with various kidney diseases. Here, we characterized proximal tubular phenotype alternations during kidney injury and repair in a mouse model of folic acid ...
Qi Yuan +8 more
doaj +1 more source

