Results 61 to 70 of about 1,749,999 (379)
Renal Failure, 2021 Background Growth differentiation factor 15(GDF15) is a distant member of the superfamily of the transforming growth factor beta (TGF-β). It has been established that increased GDF15 levels are associated with an increased risk of cardiovascular disease.
Lulu Wang +7 more
doaj +1 more source
Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]
arXiv, 2023 While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv
Ferroptosis and kidney disease
Nefrología (English Edition), 2020 Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Alberto Ortiz +8 more
openaire +4 more sources
Porphyria and kidney diseases [PDF]
Clinical Kidney Journal, 2018 The kidneys, after the bone marrow and liver, are third in terms of the amounts of haem synthesized daily. Haem is incorporated into haemoproteins that are critical to renal physiology. In turn, disturbances in haem metabolism interfere with renal physiology and are tightly interrelated with kidney diseases.
Eric Thervet +7 more
openaire +4 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
BMC Research Notes, 2018 Objective Sucroferric oxyhydroxide, a novel iron-based phosphate-binder, has been shown to have beneficial effects in lowering serum phosphorus levels and improving renal anemia in clinical studies.
Hisato Shima +4 more
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Renal Replacement TherapyBackground Cinacalcet hydrochloride (cinacalcet), an oral calcimimetics for secondary hyperparathyroidism (SHPT), has been widely used worldwide. In contrast, evocalcet, an improved derivative of cinacalcet, was approved only in Japan in 2018 and has not
Nobuo Nagano +9 more
doaj +1 more source
Advanced Science, 2022 Direct contact of membrane molecules and cytokine interactions orchestrate immune homeostasis. However, overcoming the threshold of distance and velocity barriers, and achieving adhesion mediated immune interaction remain difficult. Here, inspired by the
Jinwen Lin +5 more
doaj +1 more source
Deep Learning for Polycystic Kidney Disease: Utilizing Neural Networks for Accurate and Early Detection through Gene Expression Analysis [PDF]
arXiv, 2023 With Polycystic Kidney Disease (PKD) potentially leading to fatal complications in patients due to the formation of cysts in kidneys, early detection of PKD is crucial for effective management of the condition. However, the various patient-specific factors that play a role in the diagnosis make it an intricate puzzle for clinicians to solve, leading to
arxiv