Results 141 to 150 of about 552,750 (375)

Apoptosis and loss of renal tissue in polycystic kidney diseases.

New England Journal of Medicine, 1995
BACKGROUND Polycystic kidney disease is characterized by the enlargement of renal cysts, interstitial fibrosis, and gradual loss of normal renal tissue in association with progressive deterioration of renal function.
David D. L. Woo
semanticscholar   +1 more source

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling

eLife, 2016
TFE-fusion renal cell carcinomas (TFE-fusion RCCs) are caused by chromosomal translocations that lead to overexpression of the TFEB and TFE3 genes (Kauffman et al., 2014).
Alessia Calcagnì, Lotte kors, Eric Verschuren, Rossella De Cegli, Nicolina Zampelli, Edoardo Nusco, Stefano Confalonieri, Giovanni Bertalot, Salvatore Pece, Carmine Settembre, Gabriel G Malouf, Jaklien C Leemans, Emile de Heer, Marco Salvatore, Dorien JM Peters, Pier Paolo Di Fiore, Andrea Ballabio   +16 more
doaj   +1 more source

Renal screening sonography—A comparative study in a Portuguese basic emergency service

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 8-16, March 2025.
Renal sonography screening aids in clinical decision‐making for patients with suspected renal colic. This study intends to compare the accuracy and pertinence of sonographic findings obtained by a sonographer in a Basic Emergency Service (BES) with that of radiologists at Referral Hospital (RH) in Portugal. Renal sonography screening was able to detect
Sérgio Miravent, Carmen Jiménez, Narciso Barbancho, Manuel Duarte Lobo, Teresa Figueiredo, Carla Gomes, Ion Ratusneac, João Mário Gonçalves, Corina Hasnas, Rui de Almeida   +9 more
wiley   +1 more source

Computation of Total Kidney Volume from CT images in Autosomal Dominant Polycystic Kidney Disease using Multi-Task 3D Convolutional Neural Networks [PDF]

arXiv, 2018
Autosomal Dominant Polycystic Kidney Disease (ADPKD) characterized by progressive growth of renal cysts is the most prevalent and potentially lethal monogenic renal disease, affecting one in every 500-100 people. Total Kidney Volume (TKV) and its growth computed from Computed Tomography images has been accepted as an essential prognostic marker for ...
arxiv  

Cystic Kidney Diseases in Sudanese Children: Pattern, Clinical Presentation, and Outcome

Sudan Journal of Medical Sciences
Background: Cystic kidney disease (CKD) can directly lead to chronic kidney disease in children. This study aims to determine the types, clinical presentation, and outcome of CKD in Sudanese children. Methods: This retrospective records-based study from
Maali Alwathig Alameen, Ebtihal Eltyeb, Rashid Ellidir   +2 more
doaj   +1 more source

The effect of elexacaftor–tezacaftor–ivacaftor on liver stiffness in children with cystic fibrosis

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Cystic fibrosis hepato‐biliary involvement (CFHBI) is a common comorbidity in patients with CF and is associated with increased morbidity and mortality. The effect of the new and highly potent CF transmembrane conductance regulator modulator therapy, elexacaftor–tezacaftor–ivacaftor (ETI), on CFHBI, is still unclear.
Stefanie Diemer, Helga Elidottir, Erik A. Eklund, Lisa I. Påhlman, Christine Hansen   +4 more
wiley   +1 more source

Automatic Segmentation of the Kidneys and Cystic Renal Lesions on Non-Contrast CT Using a Convolutional Neural Network [PDF]

arXiv
Objective: Automated segmentation tools are useful for calculating kidney volumes rapidly and accurately. Furthermore, these tools have the power to facilitate large-scale image-based artificial intelligence projects by generating input labels, such as for image registration algorithms.
arxiv  

Co‐existing monophasic teratoma and uterine adenocarcinoma in a female dog [PDF]

, 2019
Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma,composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females.
Catarino, J.C, Faim, S., Freire, A., Neves, T., Orge, L., Payan-Carreira, R., Pires, M.A., Seixas, F., Vilhena, H.   +8 more
core   +2 more sources

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source