Results 191 to 200 of about 542,680 (355)

Case Report: A renal wasting disease caused by a pure deletion of nephrocystin-1. [PDF]

Front Pediatr
Dong T, Luo J, Sun T, Wu H, Zhao Q, Ma L, Yang J.   +6 more
europepmc   +1 more source

“When my mind hurts, my body hurts”: Complex PTSD and chronic physical health conditions—A qualitative study exploring the factors contributing to their relationship

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Complex PTSD (cPTSD) has a high comorbidity rate with chronic physical health conditions. This is the first qualitative study to investigate what factors might be contributing to this relationship. Methods Twelve participants with cPTSD and chronic physical health conditions were recruited from mental health services across London ...
Laura Blackett, Polly Radcliffe, Teuta Rexhepi‐Johansson, Nicola Reynolds   +3 more
wiley   +1 more source

The spectrum of diseases, genetic landscape and new mutation sites of hereditary cystic kidney disease. [PDF]

Clin Kidney J
Bi J, Guo W, Ji P, Li S, Wang P, Li Q, Xie Y.   +6 more
europepmc   +1 more source

Wnt signalling in kidney diseases: dual roles in renal injury and repair

Journal of Pathology, 2013
Takahisa Kawakami, S. Ren, J. Duffield
semanticscholar   +1 more source

Defining the polycystin pharmacophore through high‐throughput screening and computational biophysics

British Journal of Pharmacology, EarlyView.
An unbiased high throughput electrophysiology screen identifies potent PKD2L1 channel inhibitors with divergent chemical composition that bind to pore fenestration receptors and stabilise their inactivated state. Abstract Background and Purpose Polycystins (PKD2, PKD2L1) are voltage‐gated and Ca2+‐modulated members of the TRP family of ion channels ...
Eduardo Guadarrama, Carlos G. Vanoye, Paul G. DeCaen   +2 more
wiley   +1 more source

Differential Diagnosis and a Novel Mutation in Birt-Hogg-Dubé Syndrome: Insights from 2 Cases. [PDF]

Am J Case Rep
Tu L, Ye Y, Zhou J, Pan Z.
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Basal Invasion of Cancer Cells Driven by Cell–Cell Interactions: An Affirmative Role of Cell Competition in Cancer Progression

Cancer Science, EarlyView.
This review article discusses the promotive role of cell competition in the basal invasion of cancer cells. ABSTRACT Cancer develops through the transformation of normal epithelial cells, followed by the expansion of hyperplastic cells within epithelial tissues and the subsequent generation of invasive cells capable of breaching the basement membrane ...
Kazuki Nakai, Eilma Akter, Shunsuke Kon
wiley   +1 more source

Biosynthesis of complement C4 messenger RNA in normal human kidney [PDF]

, 1989
Bevec, Dorian, Felber, E., Feucht, Helmut E., Lang, M., Riethmüller, Gert, Weiss, Elisabeth H., Zwirner, Jörg   +6 more
core   +1 more source

Polycystic kidney disease

Nature Reviews Disease Primers, 2017
C. Bergmann, L. Guay-Woodford, P. Harris, S. Horie, D. Peters, V. Torres   +5 more
semanticscholar   +1 more source