Results 41 to 50 of about 542,680 (355)

Cystic kidney diseases: learning from animal models.

Nephrology, Dialysis and Transplantation, 2004
Renal tubular cysts arise in several inherited human disorders which include autosomal dominant polycystic kidney disease (ADPKD), as well as rarer disorders such as autosomal recessive polycystic kidney disease (ARPKD) nephronophthisis and medullary ...
Evelyne Fischer, L. Gresh, A. Reimann, M. Pontoglio   +3 more
semanticscholar   +1 more source

Ciliopathies and the Kidney: A Review.

American Journal of Kidney Diseases, 2020
Primary cilia are specialized sensory organelles that protrude from the apical surface of most cell types. Over the past two decades, they have been found to play important roles in tissue development and signal transduction, with mutations in ciliary ...
Dominique J. Mcconnachie, J. Stow, A. Mallett   +2 more
semanticscholar   +1 more source

CYSTIC DISEASE OF THE KIDNEYS IN CHILDREN [PDF]

American Journal of Roentgenology, 1967
A classification of renal cysts is presented with a discussion of the clinical, pathologic anti roentgenologic features.
John M. Kissane, David C. Gleason, William H. McAlister   +2 more
openaire   +3 more sources

A rare cause of recurrent spontaneous pneumothorax: Birt-hogg-dube syndrome [PDF]

, 2018
Birt-Hogg-Dube (BHD) syndrome is an unusual disorder characterized by the triad of cutaneous lesions, renal tumors and lung cysts. In cases with BHD syndrome, the frequency of recurrent pneumothorax is increased due to presence of multiple lung cysts. It
Demirci, M., Karaman, Engin, Ufuk, F., Yavaş, H.G.   +3 more
core   +1 more source

Emerging Therapies for Childhood Polycystic Kidney Disease

Frontiers in Pediatrics, 2017
Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype.
William E. Sweeney, Ellis D. Avner
doaj   +1 more source

Acquired cystic disease and renal cell carcinoma in hemodialysis patients: A case report on three patients [PDF]

Vojnosanitetski Pregled, 2015
Introduction. Renal cell carcinoma (RCC) is derived from renal tubular epithelial cells and represents approximately 3.8% of all malignancies in adults. The incidence of renal cell carcinoma has been growing steadily and ranging from 0.6 to 14.7
Mijušković Mirjana, Milović Novak, Kovačević Božidar, Jovanović Dragan, Stefanović Dara, Ignjatović Ljiljana, Terzić Brankica, Tadić-Pilčević Jelena, Petrović Marijana, Pilčević Dejan, Obrenčević Katarina, Cerović Snežana   +11 more
doaj   +1 more source

CystAnalyser: A new software tool for the automatic detection and quantification of cysts in Polycystic Kidney and Liver Disease, and other cystic disorders.

PLoS Computational Biology, 2020
The Polycystic Kidney Disease (PKD) is characterized by progressive renal cyst development and other extrarenal manifestation including Polycystic Liver Disease (PLD).
Adrián Cordido, Eva Cernadas, Manuel Fernández-Delgado, Miguel A García-González   +3 more
doaj   +1 more source

Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion

Molecular Medicine, 2023
Background Autosomal dominant polycystic kidney disease (ADPKD) is one of the most prevalent monogenic human diseases. It is mostly caused by pathogenic variants in PKD1 or PKD2 genes that encode interacting transmembrane proteins polycystin-1 (PC1) and ...
Elizabeth J. Wilk, Timothy C. Howton, Jennifer L. Fisher, Vishal H. Oza, Ryan T. Brownlee, Kasi C. McPherson, Hannah L. Cleary, Bradley K. Yoder, James F. George, Michal Mrug, Brittany N. Lasseigne   +10 more
doaj   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun, Lingling Cui, Robert Terkeltaub, Ying Chen, Xinde Li, Xiaoyu Cheng, Tian Liu, Nicola Dalbeth, Changgui Li   +8 more
wiley   +1 more source

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R., Alvarado, A., Lakshmanaperumal, N., McClain, M., McKinney, S., Rink, J., Vu, H.   +6 more
core   +1 more source