Results 71 to 80 of about 542,680 (355)

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Systematic review of transition models for young people with long-term conditions: A report for NHS Diabetes. [PDF]

open access: yes, 2013
Aims For many young people with Type 1 diabetes, transition from paediatric to adult care can result in a marked deterioration in glycaemic control.
Bagnall, A, Day, R, Kime, NH
core  

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

open access: yes, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev   +6 more
core   +1 more source

Seeing inside the Body Using Wearable Sensing and Imaging Technologies

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores wearable technologies for noninvasive internal health monitoring. It categorizes approaches into indirect sensing (e.g., bioelectrical and biochemical signals) and direct imaging (e.g., wearable ultrasound and EIT), highlighting multimodal integration and system‐level innovation toward personalized, continuous healthcare.
Sumin Kim   +3 more
wiley   +1 more source

A Clinical Prediction Score to Guide Referral of Elderly Dialysis Patients for Kidney Transplant Evaluation. [PDF]

open access: yes, 2017
IntroductionDialysis patients aged ≥70 years derive improved life expectancy through kidney transplantation compared to their waitlisted counterparts, but guidelines are not clear about how to identify appropriate transplantation candidates. We developed
Campbell, Kellie Hunter   +5 more
core   +2 more sources

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

open access: yesAdvanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song   +9 more
wiley   +1 more source

Ethical qualms about genetic prognosis [PDF]

open access: yes, 2016
The debate about direct-to-consumer genetic testing has centred on whether consumers are the best judges of their own clinical care. Inthis article, I also examine whether the science of personalized medicine is really as advanced as its proponents
Dickenson, Donna
core   +1 more source

Localized cystic kidney disease: a case report unveiling clinical and histopathological challenges

open access: yesAutopsy and Case Reports
Localized cystic kidney disease (LCKD) is a distinct renal disorder characterized by the presence of cysts within specific regions of the kidneys. We present a rare case of a 41-year-old African American man, who presented to our medical center with ...
Teresita Mendez   +8 more
doaj   +1 more source

Having Multiple Renal Cysts in a Young Adult is Not Always a Sign of Polycystic Kidney Disease

open access: yesBalkan Journal of Medical Genetics, 2022
Multiple renal cysts in adult patients could have asymptomatic, benign and a nonprogressive course. However, these cysts could be renal features of a very rare hereditary, progressive syndrome defined as cranioectodermal dysplasia (CED or Sensenbrenner ...
Kaynar K   +3 more
doaj   +1 more source

Mutations causing medullary cystic kidney disease type 1 (MCKD1) lie in a large VNTR in MUC1 missed by massively parallel sequencing

open access: yesNature Genetics, 2013
Although genetic lesions responsible for some mendelian disorders can be rapidly discovered through massively parallel sequencing of whole genomes or exomes, not all diseases readily yield to such efforts.
Andrew W. Kirby   +42 more
semanticscholar   +1 more source

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