Results 151 to 160 of about 10,805,577 (430)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Changes in the Spectrum of Kidney Diseases: An Analysis of 40,759 Biopsy-Proven Cases from 2003 to 2014 in China

open access: yesKidney Diseases, 2017
Objectives: To evaluate the changing spectrum of kidney diseases over time in China using renal biopsy-proven cases. Methods: All patients over the age of 14 years who were diagnosed with a kidney disease by renal biopsy in the Renal Biopsy Registry of ...
Jin-Hua Hou   +10 more
semanticscholar   +1 more source

Kidney disease in cardiology [PDF]

open access: yesNephrology Dialysis Transplantation, 2006
Topics covered in this review include the relation of estimated glomerular filtration rate, proteinuria and outcome; sudden cardiac death; contrast-induced acute kidney injury (CI-AKI); imaging; clinical trials targeting cardiovascular disease in chronic kidney disease (CKD) patients; and treatment of ischemic heart disease and valvular disease ...
openaire   +13 more sources

Percutaneous insertion of peritoneal dialysis catheter is a safe and effective technique irrespective of BMI

open access: yesBMC Nephrology, 2020
Background A large body mass index (BMI) has been considered as a relative contraindication for percutaneous catheter insertion, although this technique has many advantages.
Dayang Xie   +11 more
doaj   +1 more source

Semi-Automatic Segmentation of Autosomal Dominant Polycystic Kidneys using Random Forests [PDF]

open access: yesarXiv, 2015
This paper presents a method for 3D segmentation of kidneys from patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency, using computed tomography (CT) data. ADPKD severely alters the shape of the kidneys due to non-uniform formation of cysts.
arxiv  

Metabolic pathways and immunometabolism in rare kidney diseases

open access: yesAnnals of the Rheumatic Diseases, 2018
Objectives To characterise renal tissue metabolic pathway gene expression in different forms of glomerulonephritis. Methods Patients with nephrotic syndrome (NS), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), systemic lupus ...
P. Grayson   +13 more
semanticscholar   +1 more source

Urinary angiostatin: a novel biomarker of kidney disease associated with disease severity and progression

open access: yesBMC Nephrology, 2019
Background This study aimed to evaluate the value of urinary angiostatin levels for assessing disease severity and progression of IgA nephropathy (IgAN).
Yuan-Yuan Xia   +7 more
doaj   +1 more source

Extracellular vesicles for acute kidney injury in preclinical rodent models: a meta-analysis

open access: yesStem Cell Research & Therapy, 2020
Introduction Extracellular vesicles (EVs), especially stem cell-derived EVs, have emerged as a potential novel therapy for acute kidney injury (AKI). However, their effects remain incompletely understood.
Chao Liu   +8 more
doaj   +1 more source

Histone Methyltransferases as Therapeutic Targets for Kidney Diseases

open access: yesFrontiers in Pharmacology, 2019
Emerging evidence has demonstrated that epigenetic regulation plays a vital role in gene expression under normal and pathological conditions. Alterations in the expression and activation of histone methyltransferases (HMTs) have been reported in ...
Chao Yu, S. Zhuang
semanticscholar   +1 more source

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