Results 131 to 140 of about 3,539,187 (313)

Chronic diseases in Australia: blueprint for preventive action [PDF]

, 2015
This paper identifies strategic priorities for taking action to prevent chronic diseases. It is the second report by the Mitchell Institute on this issue.
Sharon Willcox, Willcox, Sharon
core  

Stem-cell therapy for renal diseases

, 2003
Significant attention is currently directed to the biological and therapeutic capabilities of stem cells for developing novel treatments for acute and chronic kidney diseases.
Mollura, Daniel J., Mollura, Daniel J, Rabb, Hamid, Hare, Joshua M, Hare, Joshua M.   +4 more
core   +1 more source

Protocol for Developing and Validating a Multimarker-Clinical Prediction Model of SGLT2 Inhibitor-Induced Acute eGFR Dip in CKD Stages 3–4: A Three-Stage Urinary Proteomics Study

Life
Introduction: SGLT2 inhibitors reduce renal composite endpoints and proteinuria, yet RCTs uniformly show an acute eGFR dip within 2 weeks to 2 months after initiation.
Zhiyu Duan, Youhe Gao, Mengjie Huang, Yanjun Liang, Jing Hao, Jie Wang, Guangyan Cai   +6 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials

, 2018
Background: Previous clinical studies of autosomal dominant polycystic kidney disease (ADPKD) reported that loss of kidney function usually follows a steep and relentless course.
Rahbari-Oskoui, Frederic F., Theodore Steinman, Jesse Wei, Schrier, Robert, Torres, Vicente E., Czarnecki, Peter, Steinman, Theodore I., Torres, Vicente, Masoumi, Amirali, Perrone, Ronald D., Rocco, Michael, Dana C. Miskulin, Yu, Alan, William E. Braun, James E. Bost, Vicente Torres, Miskulin, Dana, Hogan, Marie C., Wetzel, Louis, Godela M. Brosnahan, Ronald Perrone, Greene, Tom, Abebe, Kaleab Z., James Glockner, Briggs, Josephine, Erick Remer, Kaleab Z. Abebe, Shayman, James, Patel, Nayana, Bost, James E., Michael F. Flessner, Mittal, Pardeep, Meyers, Catherine M., Berenice Gitomer, Nayana Patel, Harris, Peter C., Kyongtae T. Bae, Franz Winklhofer, Saul Nurko, Connie Wang, Bae, Kyongtae T., Josephine Briggs, Peter C. Harris, William Henrich, Henrich, William, Wendler, David, Marie C. Hogan, Glockner, James, Vicente E. Torres, Grantham, Jared J., Nurko, Saul, King, Bernard, Dana Miskulin, Chapman, Arlene B., Miskulin, Dana C., Kelleher, Cass, Peter Czarnecki, Miller, J. Philip, Kyongtae Bae, Moore, Charity G., Robert W. Schrier, Peter McCullough, Jared Grantham, Frederic F. Rahbari-Oskoui, Theodore I. Steinman, Amirali Masoumi, McCullough, Peter, Cass Kelleher, Winklhofer, Franz, Frederic Rahbari-Oskoui, Tom Greene, Martin, Diego, Leonard, Mary, Ivan Pedrosa, Ronald D. Perrone, Godela Brosnahan, Diego Martin, Star, Robert, William Braun, Robert Star, Moe, Sharon, Charity G. Moore, Mary Leonard, Gitomer, Berenice, El-Zoghby, Ziad, Wang, Connie, Chapman, Arlene, Bernard King, James Shayman, Arlene Chapman, Peter Harris, Halin, Neil, Brosnahan, Godela M., Thompson, Paul A., Jared J. Grantham, J. Philip Miller, Schrier, Robert W., Michael Flessner, Flessner, Michael F., Paul A. Thompson, Robert Schrier, Bae, Kyongtae, Braun, William E., Alan Yu, Louis Wetzel, Catherine M. Meyers, Neil Halin, Ziad El-Zoghby, Remer, Erick, Sharon Moe, David Wendler, Pedrosa, Ivan, Arlene B. Chapman, Pardeep Mittal, Wei, Jesse, Michael Rocco   +115 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

The kidney in systemic autoimmune diseases /

, 2008
This volume brings together an international group of clinicians and clinical scientists to contribute to a state-of the-art review of the underlying pathogenic mechanisms, methods of clinical assessment, classification and diagnosis of renal disease ...
Pusey, C. D., Mason, Justin C.
core  

GENDER AND AGE DISTRIBUTION, AND URINARY METABOLIC ABNORMALITIES IN PATIENTS WITH RECURRENT URINARY TRACT STONES

Gomal Journal of Medical Sciences, 2015
Background: Urolithiasis is one of the most common urological disorders. Patients with recurrent urinary tract stones may have underlying metabolic abnormality. The objectives of this study were to determine the gender and age distribution, and frequency
Muhammad Naeem, Tariq Ahmad, Muhammad Kamran Khan, Hazrat Ullah   +3 more
doaj  

Kidney size and its correlation with demographics: a retrospective CT Scan-based study from Pakistan

The Egyptian Journal of Radiology and Nuclear Medicine
Background Kidney size is a critical parameter in the assessment of renal health, yet population-specific reference values are lacking for Pakistan. This study aimed to establish normative computed tomography (CT)-based renal dimensions and volumes in a ...
Muhammad Rashid Asghar, Faiza Mukhtar, Muhammad Shahzil, Wajahat Ali, Aimon Riaz, Ashar Yaqub, Ahmed Sheraz, Khuram Bashir, Nayyar Saleem   +8 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source