Results 231 to 240 of about 699,427 (305)

Machine learning prediction and SHAP interpretability analysis of heart failure risk in patients with hyperuricemia. [PDF]

Front Cardiovasc Med
Gan TM, Wang SR, Mo GL, Li SH, Lu YQ, Li JY.   +5 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Digoxin Toxicity in Renal Failure: Resolution With Plasma Exchange After Fab Therapy Failure. [PDF]

Cureus
Williams JM, Reddy P.
europepmc   +1 more source

Left ventricular assist device implantation in advanced kidney disease. [PDF]

JHLT Open
French BN, Nakirikanti AS, Kusher I, Wittersheim K, Vega JD, Daneshmand M, Gupta D.   +6 more
europepmc   +1 more source

Safety and Clinical Outcomes of Transvenous Lead Extraction for Cardiac Device Infections in the Very Elderly. [PDF]

J Arrhythm
Sawalha K, Marenco JP, Epstein LM, Pundlik S, Gobeil K, Fox M, Chalhoub F.   +6 more
europepmc   +1 more source

Urinothorax and pleural fluid creatinine: a retrospective analysis of pleural fluid studies at a tertiary care center and a review of the literature. [PDF]

J Thorac Dis
Shayani KE, Schwartz J, Oslance N, Wilson B, Ishikawa O, Mahmoud O, Lakticova V.   +6 more
europepmc   +1 more source

Diabetes Mellitus and Chronic Kidney Disease: The Future Is Being Surpassed. [PDF]

J Clin Med
Martínez-Castelao A, Górriz JL, Fernández-Fernández B, Soler MJ, Navarro-González JF.   +4 more
europepmc   +1 more source

Chronic health condition and risk of suicidal behaviours in two hospitals in Ghana. [PDF]

BMC Public Health
Onomah R, Osei-Bonsu P, Asare-Doku W, Oti-Boadi M, Osafo J.   +4 more
europepmc   +1 more source