Pathophysiology of Wound Development and Chronicity in Renal Disease: A Narrative Review. [PDF]
Sandepudi K+6 more
europepmc +1 more source
Advanced Microfluidics for Single Cell‐Based Cancer Research
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro+10 more
wiley +1 more source
Hepato-Renal Crosstalk in Acute and Chronic Disease: From Shared Pathways to Therapeutic Targets. [PDF]
Clementi A+8 more
europepmc +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu+12 more
wiley +1 more source
Psychological Distress and Kidney Failure as Predictors of Chemoradiotherapy Toxicity and Quality of Life in Patients with Head and Neck Cancer. [PDF]
Stan DJ+6 more
europepmc +1 more source
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang+8 more
wiley +1 more source
Prognostic factors and nutritional support in menopausal women with chronic heart failure. [PDF]
Ma L, Yang Z.
europepmc +1 more source
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu+16 more
wiley +1 more source
Burden of heart failure attributable to chronic kidney disease in older adults (1990-2021): an analysis from the global burden of disease study. [PDF]
Liu W+5 more
europepmc +1 more source