Results 31 to 40 of about 571,490 (310)

Genome-wide association and functional follow-up reveals new loci for kidney function [PDF]

open access: yes, 2012
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and stratified for key CKD risk factors. We uncovered 6 new
Döring, Angela   +999 more
core   +1 more source

L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China

open access: yesFrontiers in Public Health
BackgroundPrevious studies have shown that the triglyceride glucose-body mass index (TyG-BMI) is associated with cardiovascular disease, stroke, and cognition. Its relationship with mental health remains underexplored.
Yanqin Li   +10 more
doaj   +1 more source

Mechanisms of calcineurin inhibitor nephrotoxicity in chronic allograft injury

open access: yes, 2012
The first successful transplantation of a human kidney was performed more than 50 years ago by Murray and colleagues in 1954 between identical twins. The success of this transplantation was due to the fact that no significant rejection occurs between ...
Ryan, Michael P.   +10 more
core   +1 more source

GRATITUDE TRAINING TO REDUCE THE DEPRESSION LEVEL AMONG THE PATIENTS WITH CHRONIC KIDNEY FAILURE UNDERGOING THE HEMODIALYSIS THERAPY

open access: yesJIP (Jurnal Intervensi Psikologi), 2023
: The purpose of the study was to investigate the effectiveness of gratitude training on reducing depression levels among patients with chronic kidney failure undergoing hemodialysis therapy. The study used a single-subject experimental design with the A-
Ahmad Fikry Ghazali   +2 more
doaj   +1 more source

Vitamin D and endothelial function in chronic kidney disease [PDF]

open access: yes, 2014
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core  

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease

open access: yes, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer   +42 more
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Frequency-reduction strategy of roxadustat in patients undergoing peritoneal dialysis: a multi-center retrospective cohort study

open access: yesFrontiers in Medicine
BackgroundAlthough dose reduction is the guideline-recommended tapering strategy for roxadustat to maintain target hemoglobin levels in peritoneal dialysis (PD) patients during the maintenance phase, reducing the administration frequency represents ...
Xi Mi   +38 more
doaj   +1 more source

Management of hyperkalaemia in acute kidney injury in a heart failure patient with patiromer

open access: yesESC Heart Failure, 2020
Aims One prevalent comorbidity of chronic heart failure (CHF) is chronic kidney disease(CKD). Hyperkalemia is associated with both CHF and CKD, which often leads to withdrawal of heart failure medications in clinical praxis. Methods and results A patient
Jonathan Slawik   +3 more
doaj   +1 more source

APOL1 Genotype, Proteinuria, and the Risk of Kidney Failure: A Secondary Analysis of the AASK (African American Study of Kidney Disease and Hypertension) and CRIC (Chronic Renal Insufficiency Cohort) StudiesPlain-Language Summary

open access: yesKidney Medicine, 2022
Rationale & Objective: Patients with a high-risk Apolipoprotein L1 (APOL1) genotype are more likely to develop chronic kidney disease and kidney failure. It is unclear whether this increased risk is entirely mediated by the development of proteinuria.
Anthony Nguyen   +2 more
doaj   +1 more source

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