Results 51 to 60 of about 571,490 (310)

Causes of kidney failure among patients undergoing maintenance hemodialysis in Somalia: a multi-center study

BMC Nephrology, 2023
Background Kidney failure is one of the leading causes of morbidity and mortality worldwide. The incidence of kidney failure in Somalia has been increasing in recent years.
Hamze Ibrahim Rage, Suleyman A Ers, Abdirazak Y Kahin, Muraad M Elmi, Abdiaziz A Mohamed, Pranaw Kumar Jha   +5 more
doaj   +1 more source

Pharmacology of Treatments and Managements of Acute and Chronic Kidney Failure

, 2023
This thesis describes the treatment of Acute and Chronic Kidney failure as well as it's management. Numerous illnesses and disorders have the potential to gradually or unexpectedly decrease kidney function.
Ebenezer, Tamunokuro Power
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The spatial analysis of diagnosed Chronic Kidney Disease in Nigeria: A case study of Edo State [PDF]

, 2012
The thesis explores the severity of diagnosed chronic kidney disease (CKD) with particular reference to its impact in Edo state, Nigeria. There has been a scarcity of studies on the prevalence and spatial patterns of CKD in developing countries even ...
Oviasu, Osaretin
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effect of high normal body mass index and its trajectory on risk of new-onset hypertension among Chinese adults: a national prospective cohort study

Frontiers in Cardiovascular Medicine
BackgroundObesity or overweight is well known to be a strong risk factor for the development of hypertension. However, the association of body mass index (BMI) within the normal range and its trajectory with new-onset hypertension in adults remains ...
Hongxue Yu, Hongxue Yu, Hongxue Yu, Hongxue Yu, Hongxue Yu, Qi Gao, Qi Gao, Yuxin Lin, Yuxin Lin, Yuxin Lin, Yuxin Lin, Yuxin Lin, Fan Luo, Fan Luo, Fan Luo, Fan Luo, Fan Luo, Pingping Li, Pingping Li, Pingping Li, Pingping Li, Pingping Li, Yuping Zhang, Yuping Zhang, Yuping Zhang, Yuping Zhang, Yuping Zhang, Jiao Liu, Jiao Liu, Jiao Liu, Jiao Liu, Jiao Liu, Ruqi Xu, Yanqin Li, Yanqin Li, Yanqin Li, Yanqin Li, Yanqin Li, Licong Su, Licong Su, Licong Su, Licong Su, Licong Su   +42 more
doaj   +1 more source

Study the activity of Tryptase And Beta 2- Microglobulin Levels In the Sera of Patients With Chronic Renal Failure And Rheumatoid Arthritis [PDF]

Kirkuk Journal of Science, 2016
This work was mainly designed to study the levels of Mast Cell Tryptase & Beta 2- Microglobulin in serum of patients with chronic renal failure (CRF), which they were in the end stage of renal disease (ESDR) depending on hemodialysis (HD) and chronic ...
Sabah H. Khorsheed, Intisar F. Mustafa, Nazar A. Naji   +2 more
doaj   +1 more source

Chronic kidney disease: regional variation in Australia [PDF]

, 2013
Chronic kidney disease (CKD) is a common and serious problem in Australia and its management can be resource intensive. Those with CKD\u27s most severe form, end-stage kidney disease (ESKD), usually require kidney replacement therapy (KRT) to ...

core  

Effect of information and telephone-guided access to community support for people with chronic kidney disease: randomised controlled trial

, 2014
BackgroundImplementation of self-management support in traditional primary care settings has proved difficult, encouraging the development of alternative models which actively link to community resources.
Peter Bower (52501), Christian Blickem, Christian Blickem (397641), Brooks Helen, Anne Rogers, Chew-Graham, C, Blakeman, T, Gerry Richardson (571072), Bower, P, David Reeves, Reeves, Davd, Blakeman, Tom, Dawson, S, Gaffney, H, Lee, V, David Reeves (164641), Mossabir Rahena, Tom Blakeman, Hannah Gaffney, Gardner Caroline, Reeves, D, Blickem, C, Victoria Lee, Bower, Peter; id_orcid, Hannah Gaffney (645995), Ivaylo Vassilev (397639), Blickem, Christian, Spackman, E, Anne Kennedy (397644), Victoria Lee (645997), Richardson, Gerry, Shoba Dawson (645999), Dawson Shoba, Helen Brooks (397642), Anne Rogers (397640), Mossabir, Rahena, Spackman, Eldon, Jariwala, P, Spackman Eldon, Shoba Dawson, Blakeman Tom, Gaffney Hannah, Gaffney, Hannah, Anne Kennedy, Praksha Jariwala, Mossabir, R, Vassilev Ivaylo, Chew-Graham Carolyn, Kennedy, A, Dawson, Shoba, Rahena Mossabir (646000), Vassilev, Ivaylo, Reeves, David, Helen Brooks, Praksha Jariwala (645998), Bower Peter, Richardson, G, Caroline Gardner, Jariwala Praksha, Brooks, Helen, Rogers, A, Reeves David, Caroline Gardner (645996), Brooks, H, Kennedy, Anne P., Peter Bower, Bower, Peter, Lee, Victoria, Carolyn Chew-Graham, Blakeman, Tom; id_orcid, Tom Blakeman (645994), Blickem Christian, Lee Victoria, Eldon Spackman, Rogers, Anne, Kennedy, Anne, Gardner, Caroline, Rogers Anne, Ivaylo Vassilev, Eldon Spackman (462402), Richardson Gerry, Gardner, C, Vassilev, I, Kennedy Anne, Rahena Mossabir, Jariwala, Praksha, Chew-Graham, Carolyn, Gerry Richardson, Carolyn Chew-Graham (615627)   +88 more
core   +1 more source

Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care? [PDF]

, 2015
Background: Use of renin-angiotensin system (RAS) blockade has become increasingly widespread driven by evidence-based guidance. There is concern about the role of these agents in the genesis of avoidable acute kidney injury (AKI).
Jean Irving, Paul E Stevens, Irving, Jean, Michael Bedford, Bedford, Michael, Stevens, Paul E., Christopher KT Farmer, Farmer, Christopher K.   +7 more
core   +1 more source