Results 101 to 110 of about 687,778 (313)

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

Advanced age affects the outcome-predictive power of RIFLE classification in geriatric patients with acute kidney injury

, 2014
The RIFLE (risk, injury, failure, loss, and end-stage) classification is widely used to gauge the severity of acute kidney injury, but its efficacy has not been formally tested in geriatric patients.
Chao, Chia-Ter;Wu, Vin-Cent;Lai, Chun-Fu;Shiao, Chih-Chung;Huang, Tao-Min;Wu, Pei-Chen;Tsai, I-Jung;Hou, Chun-Cheng;Wang, Wei-Jie;Tsai, Hung-Bin;Lin, Yu-Feng;Chiang, Wen-Chih;Lin, Shuei-Liong;Tsai, Pi-Ru;Ko, Wen-Je;Wu, Ming-Shiou;Wu, Kuan-Dun, 吳明修 ;林裕峯 ;賴俊夫 ;蔡宜蓉 ;趙家德 ;姜文智 ;柯文哲 ;吳允升 ;吳寬墩 ;黃道民 ;林水龍 ;蔡壁如 ;蔡宏斌   +1 more
core   +1 more source

Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]

, 2005
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders, Ninichuk, Volha, Anders, Hans-Joachim, Volha Ninichuk   +3 more
core   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Accelerometer-derived moderate-to-vigorous physical activity and incident nonalcoholic fatty liver disease

BMC Medicine
Background The liver effects of concentrated vs. more evenly distributed moderate-to-vigorous physical activity (MVPA) patterns remain unclear. We aimed to examine the association of accelerometer-measured MVPA and different MVPA patterns with liver ...
Mengyi Liu, Ziliang Ye, Yuanyuan Zhang, Panpan He, Chun Zhou, Sisi Yang, Yanjun Zhang, Xiaoqin Gan, Xianhui Qin   +8 more
doaj   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer, Christian Fork (70601), Brandes, Ralf P., Brandes, Ralf, Schäfer, Liliana, Pavenstädt, Hermann, Kerstin Amann, Felix Jansen, Kerstin Sander (481042), Jung, Oliver, Ralf P Brandes, Holger Stark, Hermann Pavenstädt, Löhn, Matthias, Oliver Plettenburg (481045), Plettenburg, Oliver, Hartmut Ruetten (481044), Felix Jansen (362745), Holger Stark (4694), Christoph Daniel (282746), Liliana Schäfer (481043), Kerstin Amann (186160), Oliver Jung (362744), Ralf P. Brandes (362753), Kerstin Sander, Oliver Jung, Fork, Christian, Babelova, Andrea, Matthias Löhn, Hermann Pavenstädt (108698), Sander, Kerstin, Ruetten, Hartmut, Oliver Plettenburg, Hartmut Ruetten, Jansen, Felix, Andrea Babelova, Christian Fork, Stark, Holger, Christoph Daniel, Matthias Löhn (171195), Andrea Babelova (362749), Daniel, Christoph, Amann, Kerstin   +42 more
core   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

Arthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P Denton, Madelon C Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury [PDF]

, 2013
Introduction: Acute kidney injury (AKI) can evolve quickly and clinical measures of function often fail to detect AKI at a time when interventions are likely to provide benefit.
Vinsonneau, Christophe, McCullough, Peter A., Thomas Ardiles, Kim, Patrick, R Gentry Wilkerson, Gernot Marx, Lissauer, Matthew E, Laskowitz, Daniel T, Nathan I Shapiro, Shapiro, Nathan I., Wilkerson, R. Gentry, Christophe Vinsonneau, Ardiles, Thomas, Robert Birkhahn, Gong, Michelle, Hackett, James, Koyner, Jay L, Ostermann, Marlies, Jing Shi, John A Kellum, Hoste, Eric A. J., Chawla, Lakhmir S., Joannes-Boyau, Olivier, Olivier Joannes-Boyau, Sean M Bagshaw, Scott Mullaney, Hoste, Eric, Kellum, John A, Kellum, John A., Wagner, Ludwig, Michael Haase, Birkhahn, Robert, Zacharowski, Kai, Hoste, Eric AJ, Michael G Walker, Al-Khafaji, Ali, Bagshaw, Sean M., Sprague, Amy M, Davison, Danielle L., Michelle Gong, Bell, Max, Gunnerson, Kyle J., Koyner, Jay L., Shi, Jing, Feldkamp, Thorsten, Jean-Louis Vincent, Davison, Danielle L, Daniel T Laskowitz, Ludwig Wagner, Walker, Michael G., Forni, Lui G., Honore, Patrick M, Marx, Germot, Matthew E Lissauer, Ali Al-Khafaji, Jay L Koyner, James Hackett, Eric AJ Hoste, Patrick Kim, Sprague, Amy M., Azra Bihorac, Honore, Patrick M., Kashani, Kianoush, Haase, Michael, Artigas, Antonio, Cely, Cynthia M, Forni, Lui G, Andrew D Shaw, Thomas Rimmelé, Shaw, Andrew D, Bagshaw, Sean M, Kyle J Gunnerson, Kai Zacharowski, Danielle L Davison, Joannidis, Michael, Patrick M Honore, Peter A McCullough, Cynthia M Cely, Marx, Gernot, Shaw, Andrew D., Lakhmir S Chawla, Rimmelé, Thomas, Antonio Artigas, Bihorac, Azra, Vincent, Jean-Louis, Laskowitz, Daniel T., Wilkerson, R Gentry, Walker, Michael G, Max Bell, Mullaney, Scott, Amy M Sprague, McCullough, Peter A, Michael Joannidis, Gunnerson, Kyle J, Cely, Cynthia M., Shapiro, Nathan I, Thorsten Feldkamp, Marlies Ostermann, Gong, Michelle Ng, Lui G Forni, Kianoush Kashani, Lissauer, Matthew E., Chawla, Lakhmir S   +102 more
core   +1 more source

The Kidney in Congestive Heart Failure [PDF]

Circulation, 1960
As a more detailed picture of the pathogenesis of salt and water retention in congestive heart failure evolves, it appears that increased tubular reabsorption of sodium occurs very early in heart disease, with further enhancement of the fluid accumulation as filtration rate decreases later in the disease process. Increase in sympathetic activity in the
openaire   +2 more sources