Results 91 to 100 of about 2,803,576 (301)
Respiratory failure: A rare complication of chronic kidney disease mineral and bone disorder
, 2019 Background: Disordered metabolism of bone and minerals is a problem frequently encountered in patients with chronic kidney disease. Early biochemical changes include altered calcium and phosphate balance, while advanced disease produces reduced bone ...
Yaxley, J, Scott, T
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The prevalence and identification of chronic kidney disease in Switzerland [PDF]
, 2015 BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
, 2014 The RIFLE (risk, injury, failure, loss, and end-stage) classification is widely used to gauge the severity of acute kidney injury, but its efficacy has not been formally tested in geriatric patients.
Chao, Chia-Ter;Wu, Vin-Cent;Lai, Chun-Fu;Shiao, Chih-Chung;Huang, Tao-Min;Wu, Pei-Chen;Tsai, I-Jung;Hou, Chun-Cheng;Wang, Wei-Jie;Tsai, Hung-Bin;Lin, Yu-Feng;Chiang, Wen-Chih;Lin, Shuei-Liong;Tsai, Pi-Ru;Ko, Wen-Je;Wu, Ming-Shiou;Wu, Kuan-Dun +1 more
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Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son +3 more
wiley +1 more source
Cell Death and DiseaseAcute kidney injury (AKI) is in rapid prevalence nowadays. Of note, the underlying mechanisms have not been clarified. Several reports showed a cluster of differentiation-44 (CD44), a cell-surface glycoprotein, might be involved in AKI. However, its role
Jiewu Huang +9 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
, 2005 Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders +3 more
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Arthritis Care &Research, EarlyView.Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok +7 more
wiley +1 more source
Re: Timing of Pregnancy after Kidney Transplantation and Risk of Allograft Failure
, 2016 The authors have investigated the risk of allograft failure due to the timing of pregnancy after kidney transplantation. Of the 21.814 women aged 15-45 who have received a first kidney-only transplant in the United States Renal Data System, 729 ...
Serkan Akıncı
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