Results 71 to 80 of about 687,778 (313)

Kidney failure, CKD progression and mortality after nephrectomy

, 2022
PURPOSE: This study tested the hypothesis that progression of chronic kidney disease (CKD) is less aggressive in patients whose primary cause of CKD was nephrectomy, compared with non-surgical causes.
Cameron, A, Lee, J, Venuthurupalli, Sree, Cameron, Anne, Diwan, Vishal, Tan, KS, Tan, Ken-Soon, Venuthurupalli, S, Gobe, Glenda C., Hoy, Wendy E., Zhang, Jianzhen, Diwan, V, Ellis, RJ, Hoy, WE, Healy, Helen G., Lee, Jeremy, Gobe, GC, Ellis, Robert J., Healy, HG, Zhang, J   +19 more
core   +1 more source

Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure [PDF]

, 2022
BACKGROUND: Sodium glucose co-transporter-2 (SGLT2) inhibitors reduce the risk of kidney and heart failure events independent of glycemic effects. We assessed whether initiation of the SGLT2 inhibitor canagliflozin guided by multivariable predicted risk ...
Tye, Sok Cin,, Perkovic, Vlado, Heerspink, Hiddo J.L., Coca, Steven G.,, Neal, B ; https://orcid.org/, Arnott, Clare,, Jongs, Niels; id_orcid, Perkovic, Vlado,, Tye, SC, Heerspink, Hiddo J. L.,, Arnott, C ; https://orcid.org/, Vart, Priya, Heerspink, HJL, Sundström, Johan,, Coca, Steven G, Jongs, Niels, Tye, Sok Cin, Mahaffey, KW, Jongs, N, Jongs, Niels,, Neal, Bruce, Mahaffey, Kenneth W, Sundström, Johan, Perkovic, V ; https://orcid.org/, Mahaffey, Kenneth W.,, Heerspink, Hiddo. J. L., Coca, SG, Arnott, Clare, Sundström, J ; https://orcid.org/, Heerspink, Hiddo J. L., Coca, Steven G., Vart, P, Mahaffey, Kenneth W., Heerspink, Hiddo JL, Vart, Priya,, Neal, Bruce,   +35 more
core   +1 more source

Kidney Transplant Failure [PDF]

Clinical Journal of the American Society of Nephrology, 2014
Kidney transplant failure is an important cause of dialysis initiation in the United States. In 2011, this group represented 4.7% of patients new to dialysis, a 30% increase in the number of patients initiating dialysis after transplant failure since 2000 ([1][1]).
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Association of iron deficiency with kidney outcome and all-cause mortality in chronic kidney disease patients without anemia

Nutrition Journal
Background Iron deficiency is prevalent in patients with chronic kidney disease (CKD), even in those without anemia. However, the effects of iron deficiency on CKD progression and all-cause mortality in non-dialysis-dependent CKD (NDD-CKD) patients ...
Hongxue Yu, Xian Shao, Zhixin Guo, Mingzhen Pang, Shan Chen, Caoxiang She, Lisha Cao, Fan Luo, Ruixuan Chen, Shiyu Zhou, Xin Xu, Sheng Nie   +11 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

U-shaped association between triglyceride-glucose index and all-cause mortality among critically ill pediatrics: a population-based retrospective cohort study

Cardiovascular Diabetology
Background Previous studies have shown that an elevated triglyceride-glucose (TyG) index was associated with all-cause mortality in both general adult individuals and critically ill adult patients.
Qi Gao, Fan Luo, Hongxue Yu, Yuxin Lin, Ruqi Xu, Pingping Li, Yuping Zhang, Jiao Liu, Licong Su, Yanqin Li   +9 more
doaj   +1 more source

Association Between New-Onset Proteinuria During Hospitalization and Cardiovascular Mortality Among Patients With Atherosclerotic Cardiovascular Disease

JACC: Advances
Background: Evidence regarding the prognostic value of new-onset proteinuria during hospitalization among patients with atherosclerotic cardiovascular disease (ASCVD) is lacking.
Licong Su, MD, Ruixuan Chen, MD, Shiyu Zhou, MD, Zhixin Guo, MS, Yanqin Li, MD, Xiaodong Zhang, MD, Fan Luo, MD, Qi Gao, MD, Yuxin Lin, MD, Lisha Cao, MS, Jiao Liu, MS, Mingzhen Pang, MD, Caoxiang She, MS, Xin Xu, MD, Sheng Nie, MD   +14 more
doaj   +1 more source

Acute kidney injury in Australia: a first national snapshot [PDF]

, 2015
Overview Acute kidney injury (AKI) is increasing in incidence globally. This report presents the first national statistical snapshot on AKI and its impact in Australia.
Australian Institute of Health and Welfare
core  

The prevalence and identification of chronic kidney disease in Switzerland [PDF]

, 2015
BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
core   +1 more source