Results 261 to 270 of about 1,022,396 (355)

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Gene-Environment Interactions Among Black Adults With Kidney Failure - Not A Straight Forward Relationship. [PDF]

Kidney Int Rep
Harding JL, Pastan SO.
europepmc   +1 more source

LOX-1, an Oxidized Low-Density Lipoprotein Receptor, Was Upregulated in the Kidneys of Chronic Renal Failure Rats.

, 2003
Tomoko Ueno, Shinya Kaname, Kenmei Takaichi, Miki Nagase, Akihiro Tojo, Maristela L. Onozato, Toshiro Fujita   +6 more
openalex   +2 more sources

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

Advanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang, Jianbing Hou, Xin Hu, Nana Hou, Minghao Xu, Yi Du, Jingyang Xu, Yongzhao Wang, Zhuohao Xie, Junbo Shi, Yundong Zhang, Hongjuan Cui   +11 more
wiley   +1 more source

Primary renal diffuse large B-cell lymphoma presenting as new-onset kidney failure. [PDF]

Pediatr Nephrol
Bertacchi M, Vasey L, Wilhelm-Bals A, Rougemont AL, Baleydier F, Parvex P.   +5 more
europepmc   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

<i>De Novo CUL3</i> Variant in a Child Presenting With Hypertension and Kidney Failure. [PDF]

Kidney Int Rep
Peremans L, Dendooven A, D'haenens E, Symoens S, Callewaert B, Decock L, Vantomme L, Vergult S, Dehoorne J, Dossche L, Prytula A, Raes A, Renson T, Snauwaert E, Van Damme T.   +14 more
europepmc   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Artificial Placenta and Artificial Womb Technologies for Lung and Kidney Failure: A Holistic Perspective. [PDF]

ASAIO J
van Galen DJM, Martins Costa A, Siche-Pantel F, Kemper R, Rochow N, Brandani M, Halfwerk FR, Arens J, ArtPlac Research Consortium.   +8 more
europepmc   +1 more source

Co-morbidity and kidney graft failure--two main causes of malnutrition in kidney transplant patients

, 2003
Ljubica Djukanović, Visnja Lezaić, R. Blagojevic, Dragana Radivojević, Milan Stošović, Nataša Jovanović, Stojanka Ristić, Sanja Simić‐Ogrizović   +7 more
openalex   +1 more source