Results 101 to 110 of about 1,603,200 (360)

Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study

Frontiers in Endocrinology
BackgroundExisting studies investigating the impact of serum calcium (Ca), phosphate (P), 25 hydroxyvitamin D (25[OH]D), and parathyroid hormone (PTH) levels on kidney function have produced inconsistent results.
Yanjun Liang, Yanjun Liang, Yanjun Liang, Shuang Liang, Dayang Xie, Dayang Xie, Xinru Guo, Chen Yang, Tuo Xiao, Kaiting Zhuang, Yongxing Xu, Yong Wang, Bin Wang, Bin Wang, Bin Wang, Zhou Zhang, Zhou Zhang, Xiangmei Chen, Yizhi Chen, Yizhi Chen, Yizhi Chen, Guangyan Cai   +21 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Changes in urine volume and serum albumin in incident hemodialysis patients. [PDF]

, 2016
IntroductionHypoalbuminemia is a predictor of poor outcomes in dialysis patients. Among hemodialysis patients, there has not been prior study of whether residual kidney function or decline over time impacts serum albumin levels.
Chou, Jason A, Eriguchi, Rieko, Kalantar-Zadeh, Kamyar, Kim, Taehee, Kovesdy, Csaba P, Mathew, Anna T, Obi, Yoshitsugu, Rhee, Connie M, Soohoo, Melissa, Streja, Elani, Tortorici, Amanda R   +10 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]

, 1973
The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L, HALGRIMSON, CHARLES G, KATZ, FRED H, LANOIS, BERNARD, PINNGGERA, WULF, POPOVTZER, MORDECAI M, ROBINETTE, JOHN, STARZL, THOMAS E   +7 more
core   +1 more source

Alterations in hematology, immunology, inflammatory markers, liver and kidney functions in periparturient Holstein-Friesian cows fed acidogenic diet. [PDF]

, 2022
Asaad A. Fares, Mohamed M. Ghanem, Yassin Abdelraof   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]

, 2020
Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H, Appel, Lawrence J, Chen, Jing, Feldman, Harold I, Go, Alan S, He, Jiang, Hsu, Chi-yuan, Hsu, Raymond K, Kusek, John W, Lash, James P, Liu, Kathleen D, McCulloch, Charles E, Navaneethan, Sankar D, Porter, Anna C, Rahman, Mahboob, Rao, Panduranga S, Tan, Thida C, Townsend, Raymond R, Wilson, F Perry, Xie, Dawei, Yang, Jingrong, Zhang, Xiaoming   +21 more
core  

Outcomes after angiography with sodium bicarbonate and acetylcysteine [PDF]

, 2018
Background: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
,, Androsenko, Maria, Bhatt, Deepak L., Brophy, Mary, Cass, Alan, Chertow, Glenn M., Conner, Todd A., Ferguson, Ryan, Gallagher, Martin, Garcia, Santiago, Jneid, Hani, Kaufman, James, McFalls, Edward O., Myles, John, Palevsky, Paul M., Parikh, Chirag R., Shunk, Kendrick, Thwin, Soe-Soe, Weisbord, Steven D., Wu, Hongsheng   +19 more
core   +1 more source

VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney

, 2022
Markus M. Rinschen, Jennifer L. Harder, Madalina E. Carter-Timofte, Luis Zanon Rodriguez, Carmen Mirabelli, Fatih Demir, Naziia Kurmasheva, Suresh Krishna Ramakrishnan, Madlen Kunke, Yifan Tan, A. Billing, Eileen Dahlke, Alexey Larionov, Wibke Bechtel‐Walz, Ute Aukschun, Marlen Grabbe, Rikke Nielsen, Erik Christensen, Matthias Kretzler, Tobias B. Huber, Christiane E. Wobus, David Olagnier, Gary Siuzdak, Florian Grahammer, Franziska Theilig   +24 more
openalex   +2 more sources