Results 101 to 110 of about 12,427,323 (309)

A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys [PDF]

, 2019
Defining cellular and molecular identities within the kidney is necessary to understand its organization and function in health and disease. Here we demonstrate a reproducible method with minimal artifacts for single-nucleus Droplet-based RNA sequencing (
Chen, Song, Gao, Derek, Gaut, Joseph, Hoshi, Masato, Jain, Sanjay, Kim, Eric H., Knoten, Amanda, Lake, Blue B., Plongthongkum, Nongluk, Salamon, Diane, Venkatesh, Ramakrishna, Vijayan, Anitha, Zhang, Kun   +12 more
core   +2 more sources

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease [PDF]

, 2014
Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidemic proportions over the next decade. Efforts have been made to improve diagnosis and management of CKD.
Argilés, Àngel, Dakna, Mohammed, Delles, Christian, Duranton, Flore, Gayrard, Nathalie, Husi, Holger, Klein, Julie, Koeck, Thomas, Lundin, Ulrika, Mischak, Harald, Mullen, William, Nkuipou-Kenfack, Esther, Weinberger, Klaus M., Zürbig, Petra   +13 more
core   +4 more sources

Estimating Baseline Kidney Function in Hospitalized Patients with Impaired Kidney Function [PDF]

Clinical Journal of the American Society of Nephrology, 2012
Summary Background and objectives Inaccurate determination of baseline kidney function can misclassify acute kidney injury (AKI) and affect the study of AKI-related outcomes. No consensus exists on how to optimally determine baseline kidney function when multiple preadmission creatinine measurements are available.
Adriana M. Hung, Edward D. Siew, Ioana Danciu, Josh F. Peterson, Manakan Srichai, Jamie P. Dwyer, Michael E. Matheny, T. Alp Ikizler, Yaping Shi, Jonathan S. Schildcrout, James P. Smith   +10 more
openaire   +3 more sources

Maternal kidney function during pregnancy: systematic review and meta‐analysis

Ultrasound in Obstetrics and Gynecology, 2019
To review systematically current literature on kidney function changes during pregnancy, in order to estimate the extent of adaptation over the course of both healthy physiological and complicated singleton pregnancies, and to determine healthy pregnancy
V. A. Lopes van Balen, T. A. G. van Gansewinkel, S. de Haas, J. Spaan, C. Ghossein-Doha, S. V. van Kuijk, J. van Drongelen, T. Cornelis, M. Spaanderman   +8 more
semanticscholar   +1 more source

Early-Life Dietary Cadmium Exposure and Kidney Function in 9-Year-Old Children from the PROGRESS Cohort

Toxics, 2020
Cadmium (Cd) is a toxic metal associated with adverse health effects, including kidney injury or disease. The aims of this study were to estimate dietary Cd exposure during childhood, and to evaluate the association of early-life dietary Cd with ...
Edna Rodríguez-López, Marcela Tamayo-Ortiz, Ana Carolina Ariza, Eduardo Ortiz-Panozo, Andrea L. Deierlein, Ivan Pantic, Mari Cruz Tolentino, Guadalupe Estrada-Gutiérrez, Sandra Parra-Hernández, Aurora Espejel-Núñez, Martha María Téllez-Rojo, Robert O. Wright, Alison P. Sanders   +12 more
doaj   +1 more source

Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury [PDF]

, 2020
Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine-glycine-aspartic acid (RGD)-binding integrins are important mediators of the pro-fibrotic response by activating latent TGF-β at sites of injury and ...
Basta, Jeannine, Griggs, David W, Prinsen, Michael J, Rauchman, Michael, Robbins, Lynn, Stout, Lisa   +5 more
core   +1 more source

Renal function assessment in adults with recurrent calcium kidney stone disease [PDF]

, 2012
The prevalence of nephrolihiasis and chronic kidney disease has risen over the past three decades, we sought to determine if person with a history of kidney stones have lower renal function relative to non stone formers.
Milladipour, Amir Hossein, Rezaei Hemami, Mohsen   +1 more
core   +1 more source

D-Serine reflects kidney function and diseases

Scientific Reports, 2019
D-Amino acids, long-term undetected enantiomers of L-amino acids, are now emerging as potential biomarkers, especially for kidney diseases. Management of chronic kidney disease (CKD), a global problem with its high prevalence and poor prognosis, is ...
A. Hesaka, Shinsuke Sakai, K. Hamase, Tatsuhiko Ikeda, Rakan Matsui, M. Mita, M. Horio, Y. Isaka, Tomonori Kimura   +8 more
semanticscholar   +1 more source

Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study

Frontiers in Endocrinology
BackgroundExisting studies investigating the impact of serum calcium (Ca), phosphate (P), 25 hydroxyvitamin D (25[OH]D), and parathyroid hormone (PTH) levels on kidney function have produced inconsistent results.
Yanjun Liang, Yanjun Liang, Yanjun Liang, Shuang Liang, Dayang Xie, Dayang Xie, Xinru Guo, Chen Yang, Tuo Xiao, Kaiting Zhuang, Yongxing Xu, Yong Wang, Bin Wang, Bin Wang, Bin Wang, Zhou Zhang, Zhou Zhang, Xiangmei Chen, Yizhi Chen, Yizhi Chen, Yizhi Chen, Guangyan Cai   +21 more
doaj   +1 more source

Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis

Pteridines, 2020
Introduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored.
Baxter-Parker Gregory, Gaddam Ravinder Reddy, Moltchanova Elena, Carr Anitra, Shaw Geoff, Chambers Stephen, Gieseg Steven P.   +6 more
doaj   +1 more source