Results 271 to 280 of about 1,603,200 (360)

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

Comparison of radioactive and non-radioactive iothalamate and hippuran to assess kidney function. [PDF]

Clin Kidney J
Mohamed AAA, Gansevoort RT, van de Merbel NC, van Londen M, de Borst MH, Zijlma R, Junier LAT, Heerspink HJL, Stevens J.   +8 more
europepmc   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Urine proteomic signatures of kidney function decline after hospitalization. [PDF]

JCI Insight
Wen Y, Menez S, Thiessen Philbrook H, Moledina D, Coca SG, Xue J, Kaufman J, Chinchillil V, Kimmel PL, Ikizler TA, Hsu CY, Kelly T, Ricardo A, Himmelfarb J, Parikh CR, ASSESS-AKI, TRIBE-AKI, and Kidney Precision Medicine Project consortia.   +17 more
europepmc   +1 more source

Association of Urinary Sodium, Potassium, and the Sodium-to-Potassium Ratio with Impaired Kidney Function Assessed with 24-H Urine Analysis

Urtė Žakauskienė, Nomeda Bratčikovienė, Ernesta Mačionienė, Lina Zabulienė, Diana Sukackienė, Aušra Linkevičiūtė, Dovile Karosiene, Valdas Banys, Vilma Miglinė, Algirdas Utkus, Marius Miglinas   +10 more
openalex   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

A Comprehensive Framework for Kidney Function Assessment: Summary of the National Institute of Diabetes and Digestive and Kidney Diseases Reimagining Kidney Function Assessment Workshop. [PDF]

Kidney Int Rep
Bjornstad P, Narongkiatikhun P, Benzing T, Fuhrman DY, Inker L, Kestenbaum B, Koyner J, Lemley K, Seegmiller J, Waikar SS.   +9 more
europepmc   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Associations of urinary phytoestrogen biomarkers with uric acid and hyperuricemia, and the mediating role of kidney function. [PDF]

Nutr J
Luan M, Tian Y, Wu X, Chen K, Hu C.
europepmc   +1 more source