Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto+8 more
core +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Primitive neuroectodermal tumor of the kidney: report of a patient
Kidney neoplasms amount to 2-3% of total neoplasms; among them, primitive neuroectodermal tumors are not common. The case of a 28-year-old female patient, with a history of bronchial asthma, who went to see the doctor because she incidentally noticed an ...
Julio Vigil Quiñones+2 more
doaj
Lymph node dissection during the surgical treatment of renal cancer in the modern era
The increasing use of routine CT scan, along with advances in imaging technology, have facilitated the early diagnosis of incidental renal masses. This has resulted in the reduction in the rate of metastatic disease diagnosis.
Guilherme Godoy+2 more
doaj +1 more source
Evaluation of the activity of the immune system and age-related tissue markers in Turquoise killifish \ud (Nothobranchius furzeri, Jubb 1971) \ud and their role in cell ageing\ud [PDF]
Currently the Turquoise Killifish is considered the best animal model suitable for aging research. \ud This annual fish, from south east Africa, shows an exceptionally adaptive behaviour to dry periods: indeed, due to this extreme environmental ...
Di Cicco, Emiliano, Rossi, Giacomo
core
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Open partial nephrectomy for a collision renal cell carcinoma in a transplant kidney: A case report
A collision tumour of the kidney is a very rare condition defined by two immediately adjacent but histologically distinct neoplasms that coexist within one organ without histological admixture. We present a collision tumour in a transplant kidney treated
Andrew Moe+3 more
doaj
Spontaneus rupture of renal cell carcinoma in anuric patient on automated peritoneal dialysis [PDF]
Introduction. Spontaneous subcapsular or perirenal hematomas are relatively uncommon but often diagnostically challenging conditions. We present the first case described in the literature of successful continuation of the full regimen of peritoneal ...
Stojšić-Vuksanović Tatjana+1 more
doaj +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source