Results 231 to 240 of about 52,972 (309)

Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 diabetes mellitus

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The exercise pressor reflex (EPR), evoked by muscle contraction, is exaggerated in male rats with type 2 diabetes mellitus (T2DM). Cerebrospinal fluid insulin and phosphoinositide 3‐kinase in the nucleus tractus solitarius levels are normal in controls and low in T2DM rats, corresponding with normal and exaggerated EPR function ...
Juan A. Estrada   +9 more
wiley   +1 more source

Comprehensive management of vulvovaginal cancers

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues   +5 more
wiley   +1 more source

Germ cell and other tumors in individuals with differences in sex development

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel   +1 more
wiley   +1 more source

Reirradiation: Standards, challenges, and patient‐focused strategies across tumor types

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Reirradiation (reRT), defined as administering a course of radiation therapy to a specific area previously irradiated, is an evolving treatment strategy for locoregionally recurrent cancer that offers significant potential and poses inherent challenges.
Arnaud Beddok   +21 more
wiley   +1 more source

Urothelial carcinoma: Perioperative considerations from top to bottom

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip   +8 more
wiley   +1 more source

Comparison of twelve‐layer concentric object (TLCO) and Line segmentations methods to determine the renal corticomedullary sodium gradient (CMSG) with a 3 T MRI

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 3, Page 1318-1325, September 2025.
Abstract Purpose 23Na MRI is a functional imaging technique that facilitates measurements of the renal corticomedullary sodium gradient (CMSG). The CMSG can be determined by a region of interest (ROI) in the renal parenchyma along the corticomedullary axis (Line method) or by dividing the renal parenchyma into concentric layers, using the twelve‐layer ...
Patrik Jan Gallinnis   +11 more
wiley   +1 more source

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