Results 171 to 180 of about 1,655,494 (303)

Pre‐clinical evaluation of a laser system with emission control based on stone vs soft tissue recognition

open access: yesBJU International, EarlyView.
Objective To evaluate the feasibility and performance of the StoneSense™ module (SSM; IPG Medical, Marlborough, MA, USA), a prototype real‐time target recognition unit integrated into a IPG Thulium Fiber Laser (TFL). Materials and Methods The SSM analyses the spectral signature of back reflected light‐emitting diode (LED) light from the target ...
Olivier Traxer   +7 more
wiley   +1 more source

Automated irrigation systems in mitigating laser‐induced temperature during simulated ureteroscopy

open access: yesBJU International, EarlyView.
Objective To compare the temperature changes with laser activation when providing irrigation with a pressure bag vs a fluid management system (FMS). Materials and Methods Benchtop experiments were performed with a LithoVue™ Elite (Boston Scientific Corp., Marlborough, MA, USA) flexible ureteroscope placed through an 11/13‐F ureteric access sheath into ...
Richard Menzies‐Wilson   +5 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

open access: yesBritish Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher   +6 more
wiley   +1 more source

Kidney stone disease: phenomenological perspectives. [PDF]

open access: yesMed Health Care Philos
Suijker CA, van Mazijk C, Roemeling S.
europepmc   +1 more source

Patients' priorities in kidney stone disease. [PDF]

open access: yesAnn R Coll Surg Engl
Popoola V   +3 more
europepmc   +1 more source

Localised Autophagy Inhibition by Nanodiamonds Potentiates Arsenic Therapy With Favourable Safety Profile in Solid Tumours

open access: yesCell Proliferation, EarlyView.
This study presents an NDs‐mediated localised combination strategy that integrates autophagy inhibition with low‐dose ATO sensitization, enabling effective tumour suppression while enhancing safety. NDs‐mediated autophagy blockade enhances ATO efficacy while minimising systemic toxicity, highlighting a promising approach for solid tumour treatment ...
Yiliu Wang   +8 more
wiley   +1 more source

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