Results 191 to 200 of about 1,655,494 (303)

Automatic classification of kidney stone components based on smartphone microscopy and the GoogLeNet model. [PDF]

BMC Urol
Du Y, Liang Y, Li P, Xu Y, Zhen X, Li L, Huang M, Zhan Y, Li G, Wu Z, Anson CHF, Zhou C, Aimaierjiang A, Chen J, Tang K, Guo Y, Guo Z, Bian J, Lai D.   +18 more
europepmc   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Neutrophil Secretory Proteins Inhibit Calcium Oxalate Crystallisation and Crystal Growth, but Promote Crystal Aggregation

Immunology, EarlyView.
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai, Paleerath Peerapen, Visith Thongboonkerd   +2 more
wiley   +1 more source

Artificial Intelligence in Kidney Stone Imaging: Enhancing Classification and Detection for Improved Diagnostic Accuracy. [PDF]

Cureus
Bachir MA, Nawathey N, Reddy AJ, Patel R.   +3 more
europepmc   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and the Risk of Periodontitis Among Adults With Osteoarthritis: A Target Trial Emulation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) may mitigate periodontal tissue breakdown through cyclooxygenase (COX) inhibition; however, their long‐term effects on the risk of periodontitis remain unclear. Methods We emulated target trials using US electronic health records (1995–2019) to compare the 5‐year risk of incident ...
Ignacio Leiva‐Escobar, Aiswarya Puzhakkara Chennas, Zoheir Alayash, Stefan Lars Reckelkamm, Birte Holtfreter, Thomas Kocher, Sebastian‐Edgar Baumeister, Michael Nolde   +7 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Antimicrobial resistance patterns in UTIs in male patients with associated kidney stone disease: a descriptive study. [PDF]

J Med Life
Popescu RI, Babita C, Proca T, Jinga V.
europepmc   +1 more source

Associations of finerenone with reduced insulin resistance in patients with type 2 diabetes and chronic kidney disease: A real‐world observational study

Journal of Diabetes Investigation, EarlyView.
This real‐world observational study enrolled 256 patients with type 2 diabetes and chronic kidney disease (T2D‐CKD). After 12 months of finerenone treatment, 45 patients completed follow‐up. Finerenone was associated with significant improvements in insulin resistance markers (HOMA‐IR, TyG index), lipid profile (LDL‐C), glycemic control (HbA1c), and ...
Xin Zhao, Bohan Liu, Ran Sun, Yaxuan Shi, Ya Liu   +4 more
wiley   +1 more source

<i>Lysimachia christinae</i> Hance Extract Mitigates Kidney Stone Formation: Association with NOX2/ROS Axis Modulation and Ferroptosis. [PDF]

Curr Issues Mol Biol
Xia L, Zhou Z, Luo C, Yang Y, Zou D, Zhang H, Hu K, Luo X.   +7 more
europepmc   +1 more source

Optimal Healthcare Contracts: Theory and Empirical Evidence

Journal of Economics &Management Strategy, EarlyView.
ABSTRACT In this paper, we investigate the contracts offered by a large healthcare purchaser to health service providers. Contracts are based on the DRG principle that all hospitalizations in a diagnosis group are reimbursed at the same rate. This principle is relaxed in practice, as in several cases, the amount reimbursed within each DRG exhibits ...
Paolo Berta, Gianni De Fraja, Stefano Verzillo   +2 more
wiley   +1 more source