Results 61 to 70 of about 114,709 (308)

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

open access: yesAdvanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu   +11 more
wiley   +1 more source

Kidney stones? It's time to rethink those meds [PDF]

open access: yes, 2016
Kidney stones? It's time to rethink those meds. Despite being recommended for ureteral stone expulsion, tamsulosin or nifedipine are no more effective than placebo.
Jarrett, Jennie B.   +2 more
core  

Non-spherical collapse of an air bubble subjected to a lithotripter pulse [PDF]

open access: yes, 2008
In order to better understand the contribution of bubble collapse to stone comminution in shockwave lithotripsy, the shockinduced and Rayleigh collapse of a spherical air bubble is investigated using numerical simulations, and the free-field collapse ...
Bailey, Michael R.   +3 more
core   +1 more source

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

open access: yesAdvanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan   +10 more
wiley   +1 more source

Efficiency of the contact antegrade electro-pulse lithotripsy in the kidney stones treatment

open access: yesВестник урологии, 2020
Introduction. There remains a need to introduce new methods of treating kidney stones, given the increasing incidence of urolithiasis. Considering the proven efficacy and safety of retrograde electro-pulse lithotripsy, its use in the treatment of stones ...
A. V. Gudkov   +3 more
doaj   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

open access: yesAdvanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma   +5 more
wiley   +1 more source

Risk of chronic kidney disease in patients with kidney stones—a nationwide cohort study

open access: yesBMC Nephrology, 2020
Background Chronic kidney disease (CKD) and kidney stones are common in Taiwan; in particular, CKD has a high prevalence but low self-awareness rate.
Tzung-Fang Chuang   +5 more
doaj   +1 more source

Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture

open access: yesAdvanced Science, EarlyView.
Matrigel remains the most widely used scaffold in organoid and 3D culture despite its murine origin, variability, and translational limitations. This review discusses the barriers to replacing Matrigel with xeno‐free alternatives and introduces practical tools, including a matrix selection checklist and scaffold assessment criteria, to guide the ...
Lisa Wolff, Sven Hendrix
wiley   +1 more source

Shock-induced collapse of a gas bubble in shockwave lithotripsy [PDF]

open access: yes, 2008
The shock-induced collapse of a pre-existing nucleus near a solid surface in the focal region of a lithotripter is investigated. The entire flow field of the collapse of a single gas bubble subjected to a lithotripter pulse is simulated using a high ...
Colonius, Tim, Johnsen, Eric
core   +2 more sources

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

open access: yesAdvanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour   +14 more
wiley   +1 more source

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