Results 71 to 80 of about 49,486 (262)

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

National analysis of the dietary index for gut microbiota and kidney stones: evidence from NHANES (2007–2018)

Frontiers in Nutrition
BackgroundPrevious studies have highlighted the effects of diet and gut microbiota on the incidence of kidney stones, and the dietary index for gut microbiota (DI-GM) is a new dietary index that accurately represents the variety of gut microbiota.
Xinzhou Yan, Xinzhou Yan, Xianhua Shao, Xianhua Shao, Tengyue Zeng, Tengyue Zeng, Qijie Zhang, Qijie Zhang, Junpeng Deng, Junpeng Deng, Jianjun Xie, Jianjun Xie   +11 more
doaj   +1 more source

Maximum Allowable Contrast Dose and Risk of Acute Kidney Injury After Coronary Procedures

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Recent studies have questioned whether iodinated contrast is causally related to acute kidney injury (AKI). AIM We pursed a contemporary analysis to determine the impact of contrast dose on AKI following coronary procedures in an era of lower contrast doses and less nephrotoxic agents.
Harshita Gaba, Elise Mesenbring, Christine Chow, Jennifer A. Rymer, Celina M. Yong, Stephen W. Waldo, Jacob A. Doll   +6 more
wiley   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

A study on the relationship between the weight-adjusted waist index and kidney stone prevalence mediated by diabetes: data from NHANES 2007–2018

Scientific Reports
This study investigated the association between the weight-adjusted waist circumference index (WWI) and the prevalence of kidney stones among U.S. adults with diabetes, addressing the knowledge gap regarding the role of central obesity in kidney stone ...
Yanfeng Su, Ruji Wu, Haofeng Yuan, Jiawei He, Huien Pan   +4 more
doaj   +1 more source

The success of extracorporeal shock wave lithotripsy at stones up to 10 mm in horseshoe kidneys

Medicine Science, 2016
Aim of this study is to research retrospectively the effectiveness of extracorporeal shock wave lithotripsy (SWL) for horseshoe kidney according to the size of stones.
Muhammet Guzelsoy, Soner Coban, Ali Riza Turkoglu, Sedat Oner, Ahmet Cumhur Kose, Murat Demirbas   +5 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

Deep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu, Dawei Cui, Yingjie Liu, Yuntao Liang, Yue Zhang   +4 more
wiley   +1 more source

Elevated albumin-bilirubin score as a predictor of kidney stones in adults with type 2 diabetes mellitus: evidence from a cross-sectional study [PDF]

PeerJ
The presence of kidney stones in individuals with type 2 diabetes mellitus (T2DM) poses a significant challenge and burden, yet the underlying pathogenesis remains elusive.
Wenya Mo, Tao Zhou, Qifei Dong, Yuhan Chen, Xuechun Hu, Jun Xiao, Changming Wang, Ping Xiang   +7 more
doaj   +2 more sources

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source